Preventing kidney damage in heatstroke patients using sodium bicarbonate
Use of Sodium Bicarbonate as Prophylaxis for Kidney Damage in Patients With Heatstroke
This study is testing if giving sodium bicarbonate to heatstroke patients can help prevent kidney damage and the need for dialysis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospital General de Mexicali Academic / other |
| Locations | 1 site (Mexicali, Estado de Baja California) |
| Trial ID | NCT06622525 on ClinicalTrials.gov |
What this trial studies
This study aims to prevent renal failure in patients suffering from rhabdomyolysis due to heatstroke by administering sodium bicarbonate. The intervention is based on previous findings that bicarbonate infusion can reduce the incidence of renal failure in similar cases. Conducted at the General Hospital of Mexicali during the summer months, the study will evaluate the effectiveness of this treatment in preventing the need for renal replacement therapy. Eligible patients will be those diagnosed with heatstroke and exhibiting specific clinical criteria.
Who should consider this trial
Good fit: Ideal candidates are patients admitted to the General Hospital of Mexicali with a diagnosis of heatstroke and elevated CPK levels.
Not a fit: Patients who do not meet the criteria for heatstroke or lack necessary serum creatinine levels may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of kidney damage in heatstroke patients.
How similar studies have performed: Previous studies have shown success with bicarbonate infusion in similar contexts, suggesting potential for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admitted to the General Hospital of Mexicali with the diagnosis of heat stroke. * Meeting the operational definition (exposure to heat, body temperature at admission greater than 40 degrees Celsius). * CPK level greater than 1000 U/L. * Having informed consent from the patient or the legally responsible adult. Exclusion Criteria: * Exclusion of the heat stroke diagnosis during their evaluation. * Lack of serum creatinine levels at the time of admission to the protocol.
Where this trial is running
Mexicali, Estado de Baja California
- Hospital General de Mexicali — Mexicali, Estado de Baja California, Mexico (Recruiting)
Study contacts
- Principal investigator: Hiram J Jaramillo Ramirez, MD — Hospital General de Mexicali
- Study coordinator: Joaquin Cordova Erberk, MD
- Email: joaquincerberk@gmail.com
- Phone: +52 653 132 0309
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.