Prevalence of central sensitization signs in adults with ASD without intellectual disability
Official title: Presca : Prospective Study to Determine the Prevalence of Signs of Central Sensitization in Adults With ASD Without Intellectual Developmental Disorders
Run by Groupe Hospitalier Mutualiste de Grenoble · NCT07495761 · Data updated 2026-11-12
This project will see how common signs of central sensitization—which can change how pain is felt—are in adults with autism spectrum disorder who do not have intellectual disability.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Groupe Hospitalier Mutualiste de Grenoble Academic / other |
| Locations | 1 site (Grenoble, Isere) |
| Status | Recruiting |
| Started | February 4, 2026 |
| Main results expected | July 29, 2027 |
| Study ends | July 29, 2027 |
| Registry record updated | March 27, 2026 |
| Trial ID | NCT07495761 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18 years or older) with a clinician-diagnosed ASD who do not have an intellectual developmental disorder, who can understand written French, can provide consent, and are affiliated with a social security system are ideal candidates.
✕Probably not a fit
People with intellectual developmental disorders who cannot complete self-administered questionnaires, those who cannot read French, or those unable to give consent are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational study enrolling adults (age 18+) who have a medical diagnosis of autism spectrum disorder without an established intellectual developmental disorder. Participants must understand written French and will complete self-administered questionnaires and have relevant clinical information recorded to identify signs consistent with central sensitization and atypical pain processing. The study aims to estimate how frequently these signs occur in this specific adult ASD population and describe associated clinical features. The work is conducted at a single site (Groupe Hospitalier Mutualiste de Grenoble) and excludes individuals unable to complete self-report measures or to give informed consent.
Why it matters
Potential benefit: If successful, the findings could improve recognition of pain-related central sensitization in adults with ASD and help clinicians tailor pain management and support.
How similar studies have gone: Prior research has documented altered sensory and pain processing in ASD, but systematic prospective estimates of central sensitization signs specifically in adults without intellectual disability remain limited, so this approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Medical diagnosis of ASD without established intellectual developmental disorder 3. Patient affiliated with a social security system or beneficiary of such a system 4. Understanding of written French (good comprehension of self-questionnaire questions) 5. No objection from the patient to participate in the study Exclusion Criteria: 1. Intellectual developmental disorder that prevents understanding of self-administered questionnaires 2. Individuals subject to legal or judicial protection measures or unable to express their consent
Where it's running
-
Groupe Hospitalier Mutualiste de Grenoble
Grenoble, Isere, France Recruiting
Study contacts
- Study coordinator: Estelle ECR Cotte Raffour, Pain Resource Nurse
- Email: estelle.cotte-raffour@avec.fr
- Phone: +33 6 60 34 61 67
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.