Presence of neurotrophic growth factors in breast milk
Official title: Evaluation of Neurotrophic Growth Factors in Breast Milk at Two Years of Age and Beyond
Run by Istanbul University · NCT05943847 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether certain brain-supporting proteins are still found in the breast milk of mothers with toddlers older than 18 months to see how they might help with brain development.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 25 (estimated) |
| Sponsor | Istanbul University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT05943847 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are mothers who have exclusively breastfed their infants for the first six months and are participating in the 18-month follow-up.
✕Probably not a fit
Mothers of infants who were not exclusively breastfed in the first six months or those with certain medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the presence of neurotrophic factors, specifically Brain-Derived Neurotrophic Factor (BDNF), S100B protein, and glial cell line-derived neurotrophic factor (GDNF), in the breast milk of mothers with 18-month-old children. It will collect breast milk samples from 25 mothers at three different time points: when their child is 18 months, 24 months, and after 25 months. The study seeks to determine whether these neurotrophic factors persist in breast milk beyond the age of 2 years, contributing to our understanding of their role in infant brain development.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of the nutritional and developmental benefits of breast milk for infants beyond the age of two.
How similar studies have gone: While the presence of neurotrophic factors in breast milk has been previously demonstrated in younger infants, this study's focus on older infants is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Mothers who applied for the 18th-month follow-up of their exclusively breastfed baby for the first 6 months agreed to participate in the study. Exclusion Criteria: * Mothers of infants who were not exclusively breastfed in the first six months * Mothers with infection, metabolic disease, central nervous system, breast disease or pregnancy * Mothers of infants with infection, metabolic disease, malnutrition and central nervous system disease * Mothers who stop breastfeeding before 25 months
Where it's running
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İstanbul University İstanbul Medical Faculty Department of Pediatrics Division of Social Pediatrics
Istanbul, Turkey Recruiting
Study contacts
- Principal investigator: Öykü Özbörü Aşkan, PhD — İstanbul Univeristy
- Study coordinator: Gonca Keskindemirci, Assoc Prof
- Email: keskindemirci@hotmail.com
- Phone: 0905324934651
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Rivaroxaban in breast milk after maternal dosing
This will test how much rivaroxaban passes into breast milk in postpartum people taking either prophylactic (10 mg) or therapeutic (20 mg) doses.
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Analyzing breast milk and feces from mother-infant pairs
This study is trying to see how the health of mothers affects the microbes in their breast milk and their babies' poop to help improve infant health.
-
Study on mother-infant gut health in Malaysia and China
This study looks at how the types of bacteria in breast milk from mothers in Malaysia and China might affect their babies' health and development during the first year of life.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.