Preoperative urine infections and colonization in older adults having bone and orthopedic surgery
Urinary Infection and Colonization in Bone Procedures
This will see if having a urinary infection or colonization before bone or orthopedic surgery raises the risk of postoperative complications in people aged 65 and older.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Tomas Bata Hospital, Czech Republic Academic / other |
| Locations | 1 site (Zlín) |
| Trial ID | NCT06896643 on ClinicalTrials.gov |
What this trial studies
Older adults (65+) undergoing elective or acute bone, trauma, or orthopedic surgery will have routine pre-anesthetic urine testing (chemical + sediment) with bacteriology if indicated. Investigators will record symptoms, fever, whether the urinary finding was treated and whether a control urine test was done, patient origin (home or social care), Clinical Frailty Scale, type of anesthesia, and any antibiotics given. During hospitalization the team will monitor for postoperative urinary infection and predefined complications including fever, circulatory instability, delirium, sepsis, and death, and will track patients' ward trajectory and length of stay. The protocol is observational and does not alter standard clinical care.
Who should consider this trial
Good fit: Ideal candidates are patients aged 65 or older undergoing elective or acute trauma/orthopedic bone surgery at the enrolling hospital who receive standard pre-anesthetic urine testing and can provide informed consent.
Not a fit: Patients under 65, those with negative preoperative urine tests, and those excluded for acute severe conditions or impaired capacity (for example delirium, coma, severe mental disorder, or septic state) are unlikely to benefit from this study's findings.
Why it matters
Potential benefit: If a clear link is found, clinicians could better identify and manage preoperative bacteriuria to lower postoperative complication risk in older surgical patients.
How similar studies have performed: Previous research on the relationship between preoperative bacteriuria and postoperative complications is limited and mixed, with some specific surgeries showing associations but no consistent consensus.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age over 65 years, including * Elective or acute trauma/orthopedic bone surgery * Urine examination as part of pre-anesthetic examination, urine + sediment, in case of suspicion - bacteriological examination * Signed informed consent for research as part of pre-anesthetic examination (I or II), respecting informed consent as an expression of the patient's "free will" Exclusion Criteria: * Negative finding in urine: chemical examination + sediment preoperatively * Respondent under the influence of premedication, alcohol, or drugs * Sensory impairment (blindness) * Delirious preoperative state * Severe mental disorder * Sopor * coma * Septic state * Acute respiratory failure * Disagreement with participation in the study
Where this trial is running
Zlín
- Tomas Bata Hospital — Zlín, Czechia (Recruiting)
Study contacts
- Study coordinator: Klára Nekvindová, M.D., Ph.D.
- Email: nekvindova.klara@gmail.com
- Phone: +420 577 551 111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.