Preoperative urine infections and colonization in older adults having bone and orthopedic surgery
Official title: Urinary Infection and Colonization in Bone Procedures
Run by Tomas Bata Hospital, Czech Republic · NCT06896643 · Data updated 2026-11-12
This will see if having a urinary infection or colonization before bone or orthopedic surgery raises the risk of postoperative complications in people aged 65 and older.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Tomas Bata Hospital, Czech Republic Academic / other |
| Locations | 1 site (Zlín) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | March 1, 2026 |
| Study ends | June 1, 2026 |
| Registry record updated | July 8, 2025 |
| Trial ID | NCT06896643 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 65 or older undergoing elective or acute trauma/orthopedic bone surgery at the enrolling hospital who receive standard pre-anesthetic urine testing and can provide informed consent.
✕Probably not a fit
Patients under 65, those with negative preoperative urine tests, and those excluded for acute severe conditions or impaired capacity (for example delirium, coma, severe mental disorder, or septic state) are unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Older adults (65+) undergoing elective or acute bone, trauma, or orthopedic surgery will have routine pre-anesthetic urine testing (chemical + sediment) with bacteriology if indicated. Investigators will record symptoms, fever, whether the urinary finding was treated and whether a control urine test was done, patient origin (home or social care), Clinical Frailty Scale, type of anesthesia, and any antibiotics given. During hospitalization the team will monitor for postoperative urinary infection and predefined complications including fever, circulatory instability, delirium, sepsis, and death, and will track patients' ward trajectory and length of stay. The protocol is observational and does not alter standard clinical care.
Why it matters
Potential benefit: If a clear link is found, clinicians could better identify and manage preoperative bacteriuria to lower postoperative complication risk in older surgical patients.
How similar studies have gone: Previous research on the relationship between preoperative bacteriuria and postoperative complications is limited and mixed, with some specific surgeries showing associations but no consistent consensus.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age over 65 years, including * Elective or acute trauma/orthopedic bone surgery * Urine examination as part of pre-anesthetic examination, urine + sediment, in case of suspicion - bacteriological examination * Signed informed consent for research as part of pre-anesthetic examination (I or II), respecting informed consent as an expression of the patient's "free will" Exclusion Criteria: * Negative finding in urine: chemical examination + sediment preoperatively * Respondent under the influence of premedication, alcohol, or drugs * Sensory impairment (blindness) * Delirious preoperative state * Severe mental disorder * Sopor * coma * Septic state * Acute respiratory failure * Disagreement with participation in the study
Where it's running
-
Tomas Bata Hospital
Zlín, Czechia Recruiting
Study contacts
- Study coordinator: Klára Nekvindová, M.D., Ph.D.
- Email: nekvindova.klara@gmail.com
- Phone: +420 577 551 111
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.