Preoperative magnetic clip versus wire localization for breast-conserving surgery in France.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

MAGNETO is a prospective, non-interventional, multicenter French study comparing two routine localization methods—magnetic clip and metallic wire—for non-palpable, unifocal breast lesions. Patients are enrolled at preoperative consultation and followed for up to six months after surgery, with baseline clinical data, quality-of-life (EQ-5D-5L), satisfaction questionnaires, and complication recording. Radiologists and surgeons complete Likert-scale satisfaction questionnaires after localization and on the day of surgery, and centers follow their usual clinical practices without assigned randomization. The primary analysis is a cost-consequence comparison between the two localization approaches using real-world practice patterns across participating centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* I1. Female aged ≥ 18 years;
* I2. Patient presenting with a unifocal and unilateral lesion of invasive carcinoma or in situ;
* I3. Indication for first breast-conserving treatment with the need for preoperative localization of the lesion, regardless of the associated lymph node procedure;
* I4. Patient affiliated with a health insurance system;
* I5. Non-opposition to the study.

Exclusion Criteria:

* E.1. Psychological, family, or sociological condition that may potentially compromise adherence to the treatment protocol and follow-up;
* E.2. Bilateral surgery required;
* E.3. Patient with metastatic breast cancer;
* E.4. Multifocal or benign lesions;
* E.5. Pregnant or breastfeeding patient;
* E.6. Need for neoadjuvant treatment;
* E.8. Patient under guardianship, curatorship, or deprived of liberty.

Where it's running

• Hospices Civils de Lyon Hopital de la Croix rousse
  Lyon, France Recruiting
• Centre Léon Bérard
  Lyon, France Recruiting
• Institut de Cancérologie de Lorraine (ICL)
  Nancy, France Recruiting
• Hôpital Nord -Ouest Val d'Oise (NOVO)
  Pontoise, France Recruiting
• Institut GODINOT
  Reims, France Recruiting
• Institut Gustave Roussy
  Villejuif, France Recruiting

Study contacts

• Study coordinator: Severine Metzger
• Email: severine.metzger@lyon.unicancer.fr
• Phone: +33 (0)4 78 78 27 86

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.