Preoperative deep parasternal intercostal plane block to reduce opioid use during median sternotomy
Official title: Preoperative Ultrasound-Guided Deep Parasternal Intercostal Plane Block Reduces Intraoperative Opioid Consumption in Adults Undergoing Cardiac Surgery Via Median Sternotomy
Run by Gaziantep City Hospital · NCT07315308 · Data updated 2026-11-12
This will test whether a bilateral ultrasound-guided deep parasternal intercostal plane (DPIP) block given before surgery can reduce opioid use during and after elective median sternotomy in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Gaziantep City Hospital Academic / other |
| Locations | 1 site (Gaziantep, Sahinbey) |
| Status | Recruiting |
| Started | February 12, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | March 4, 2026 |
| Trial ID | NCT07315308 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 to 65 scheduled for elective cardiac surgery via median sternotomy who can undergo general anesthesia and provide informed consent.
✕Probably not a fit
Patients on long-term opioid therapy, with coagulation disorders or local infection, those undergoing emergency surgery, or with severe cognitive impairment are unlikely to benefit or are excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, randomized controlled trial enrolling adults scheduled for elective cardiac surgery via median sternotomy. Participants will be randomized to receive a bilateral ultrasound-guided DPIP block after induction of general anesthesia plus standardized multimodal analgesia, or to receive standardized multimodal analgesia alone. The primary outcome is intraoperative opioid consumption, with secondary outcomes likely including postoperative pain scores, time to extubation, nausea/vomiting, and ICU length of stay. The study is single-center and conducted at Gaziantep Sehir Hastanesi in Gaziantep, Turkey.
Why it matters
Potential benefit: If successful, the DPIP block could lower intraoperative and postoperative opioid requirements, potentially enabling faster extubation, less nausea, and shorter ICU stays.
How similar studies have gone: Other thoracic plane and parasternal blocks have shown opioid-sparing effects in small studies, but the DPIP block itself is relatively new and lacks extensive high-quality randomized data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adults aged 18 to 65 years Scheduled to undergo elective cardiac surgery via median sternotomy Planned general anesthesia Able to provide written informed consent Exclusion Criteria: Known allergy or contraindication to local anesthetics Coagulation disorders or ongoing anticoagulant therapy that contraindicates regional anesthesia Infection at or near the planned injection site Pre-existing chronic pain conditions requiring long-term opioid use Severe cognitive impairment or inability to communicate pain intensity Emergency surgery Refusal or inability to provide informed consent
Where it's running
-
Gaziantep Sehir Hastanesi
Gaziantep, Sahinbey, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Burak Cemil BALIK, MD
- Email: cburakbalik@hotmail.com
- Phone: 905339545102
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.