Prehabilitation program to improve heart rate variability in cancer surgery patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of a multimodal prehabilitation program designed for cancer patients scheduled for major abdominal or thoracic surgery. The program aims to enhance patients' functional capacity and ability to cope with physiological stress before surgery through interventions such as exercise, nutrition, and psychological support. Heart rate variability (HRV) will be used as an objective measure to assess the impact of prehabilitation on patients' recovery and surgical outcomes. The study is a multicenter, randomized trial involving chronic cancer patients across multiple international locations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Scheduled to undergo elective major abdominal or thoracic cancer surgery;
2. Scheduled to undergo surgery at least three weeks after enrollment;
3. Age ≥ 18 years;
4. Provide written informed consent;
5. Willing and able to use smartphone application.

Exclusion Criteria:

1. Presenting with very poor functional capacity;
2. American Society of Anesthesiologists (ASA) physical status classes 5-6;
3. Disabling orthopedic, neuromuscular, and psychiatric diseases or other conditions that preclude participation in a prehabilitation program.

Where it's running

• Università di Foggia
  Foggia, Italy Recruiting
• IRCCS Ospedale San Raffaele
  Milan, Italy Recruiting
• Azienda Ospedaliero Universitaria Pisana
  Pisa, Italy Recruiting
• Azienda Ospedaliero Universitaria Policlinico San Marco di Catania
  Catania, Italy Active not recruiting

Study contacts

• Principal investigator: Fabio Guarracino, Doctor — Azienda Ospedaliero, Universitaria Pisana
• Study coordinator: Fabio Guarracino, Dr
• Email: f.guarracino@ao-pisa.toscana.it
• Phone: +393281652528

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.