Pregnancy in people with inflammatory bowel disease
Pregnancy and Inflammatory Bowel Disease
This project will see if pregnancy changes how often women with IBD have disease flares by analyzing registry data from women who had pregnancies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 945 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Trial ID | NCT07377188 on ClinicalTrials.gov |
What this trial studies
This is a retrospective observational analysis using the EPIMAD registry to describe IBD course before, during, and after pregnancy in 945 women. Investigators will cross-link IBD history with pregnancy, postpartum, and breastfeeding data to count flares and timing of disease activity. Eligible participants are women aged 18–50 diagnosed with Crohn's disease or ulcerative colitis between 1988 and 2018 who lived in the Somme and had at least one pregnancy. No interventional treatments are given as part of this project; it uses existing registry records from CHU Amiens.
Who should consider this trial
Good fit: Women aged 18–50 with a confirmed diagnosis of Crohn's disease or ulcerative colitis recorded in the EPIMAD registry who live in the Somme and have had at least one pregnancy.
Not a fit: Women who have never been pregnant, who are not included in the EPIMAD registry, or who live outside the Somme region are unlikely to be included or directly benefit from this analysis.
Why it matters
Potential benefit: If successful, the findings could help clinicians better predict flare risk during pregnancy and tailor monitoring and treatment plans for pregnant people with IBD.
How similar studies have performed: Previous cohort and registry studies have examined pregnancy and IBD with mixed but informative results, so this work adds regional and longitudinal data rather than testing a wholly novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * women between 18 and 50 years old * MICI diagnosed between 1988 and 2018 * included in EPIMAD registry * living in Somme * having had at least one pregnancy Exclusion Criteria: * women who has not had pregnancy * not included in EPIMAD register
Where this trial is running
Amiens
- CHU Amiens — Amiens, France (Recruiting)
Study contacts
- Study coordinator: Arthur FOULON, Pr
- Email: foulon.arthur@chu-amiens.fr
- Phone: 33+3 22 08 73 82
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.