Pregnancy 24/7 Offspring: tracking infant growth and heart-risk after pregnancy
Official title: Sedentary Behavior, Physical Activity, and 24-hour Behavior in Pregnancy and Offspring Health: the Pregnancy 24/7 Offspring Study
Run by University of Iowa · NCT07172880 · Data updated 2026-11-12
This project will test whether a pregnant person's daily activity, sitting time, and sleep across pregnancy are linked to their child's growth, body fat, and early heart-disease risk up to age 2.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years to 47 Years |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | University of Iowa Academic / other |
| Locations | 3 sites (Iowa City, Iowa and 2 other locations) |
| Status | Recruiting |
| Started | July 1, 2023 |
| Main results expected | May 30, 2027 |
| Study ends | May 30, 2027 |
| Registry record updated | November 2, 2026 |
| Trial ID | NCT07172880 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are people enrolled in the Pregnancy 24/7 cohort who provided at least one valid 24-hour activity/sleep monitor recording during pregnancy and had a singleton live birth.
✕Probably not a fit
Families whose child has congenital or chromosomal conditions that affect growth or cardiovascular risk, or who did not complete the required prenatal monitoring, are unlikely to benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multi-site observational cohort follows participants from the Pregnancy 24/7 study and adds standardized offspring measurements through 24 months. Maternal 24-hour behaviours (sedentary time, physical activity, and sleep) were measured objectively in each trimester using wearable monitors. Offspring outcomes include growth, adiposity, and early cardiovascular risk markers, with exclusion of children with major congenital or chromosomal abnormalities. The work leverages harmonized data from University of Iowa, University of Pittsburgh, and West Virginia University and is supported by the National Heart, Lung, and Blood Institute.
Why it matters
Potential benefit: If successful, this could identify pregnancy behaviours that can be changed to lower children's obesity and early cardiovascular risk.
How similar studies have gone: Previous work links maternal obesity, smoking, diet, and gestational weight gain to offspring risk, but using objective 24-hour monitoring of activity and sleep in pregnancy to predict child growth and early cardiovascular risk is relatively novel and not yet widely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Maternal Inclusion Criteria: * Enrolled in Pregnancy 24/7 Study. * Completed at least one 24-hr behavior assessment, with valid objective activity monitor data and questionnaires. * Pregnancy resulted in singleton live birth. Offspring Exclusion Criteria: -Child diagnosed with congenital or chromosomal abnormalities that may affect growth or CVD risk.
Where it's running
-
University of Iowa
Iowa City, Iowa, United States Recruiting -
West Virginia University
Morgantown, West Virginia, United States Recruiting -
University of Pittsburgh
Pittsburgh, Pennsylvania, United States Active not recruiting
Study contacts
- Principal investigator: Kara M Whitaker, PhD, MPH — University of Iowa
- Study coordinator: Kara M Whitaker, PhD, MPH
- Email: kara-whitaker@uiowa.edu
- Phone: 319-335-7907
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.