Predictive test for preterm birth in threatened preterm labor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the Premaquick test with the PARTOSURE test to predict preterm delivery in women with threatened preterm labor between 24 and 33+6 weeks of gestation. It is an interventional investigation evaluating prognosis-based testing rather than a treatment. Eligible participants are adults with singleton pregnancies and recent uterine contractions, who meet specific ultrasound and clinical criteria. The study is led by University Hospital Strasbourg, with recruitment at Hôpitaux Universitaires de Strasbourg, and uses the two biomarker-based tests to inform risk of preterm birth. Results could guide clinical decisions and management in threatened preterm labor cases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient aged \> 18 years (with no upper age limit)
* Patient affiliated to a social security health regime
* Between 24 and 33 + 6 weeks of gestation (amenorrhea)
* Singleton pregnancy
* Patient with a TPL: Uterine contractions during the last 24 hours felt by the patient, painful or not, and cervix less than or equal to 25 mm on endovaginal ultrasound
* Having signed an informed consent form

Exclusion Criteria:

* Twin pregnancy
* Sexual intercourse less than 24 hours from inclusion
* Cervical cerclage
* Abundant metrorrhagia
* Premature rupture of membranes
* Pre-eclampsia
* Congenital malformation
* Presence of a placenta previa
* Pelvic examination in the previous 24 hours (compared to inclusion)
* Patient under guardianship, curatorship or safeguard of justice
* Persons deprived of their liberty by judicial or administrative decision
* Persons under psychiatric care under duress

Where it's running

• Hôpitaux Universitaires de Strasbourg
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: Antoine KOCH, PHD
• Email: antoine.koch@chru-strabourg.fr
• Phone: +33 3 88 12 75 03

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• PremaSure: a self-test to check the risk of preterm delivery in symptomatic pregnant patients.

  This will test whether the PremaSure self-test can tell symptomatic pregnant patients if they are likely to deliver within 7 or 14 days.

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• Higher-dose versus standard-dose aspirin to prevent another early preterm birth

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• Evaluating a device to predict preterm birth risk in pregnant women

  This study is testing a new device to see if it can help predict the risk of preterm birth in pregnant women who are having early labor symptoms.

  Recruiting at 4 sites Ultrasound-Innovation Medtech, S.L. · A Coruña and 13 other locations · NCT06968364

• Monitoring blood glucose in pregnant women receiving betamethasone for fetal lung development

  This study looks at how the medication betamethasone affects blood sugar levels in pregnant women who don't have diabetes but are at risk of preterm birth.

  Recruiting University of Aarhus · Aarhus, Central Region Denmark · NCT06794307

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.