Prediction model for heart and brain complications in elderly patients after non-cardiac surgery

Construction of a Prediction Model for Severe Cardiovascular and Cerebrovascular Complications in Elderly Patients After Elective Non-cardiac Surgery: a Prospective Cohort Study

Observational Beijing Tsinghua Chang Gung Hospital · NCT06391632

This study is trying to create a tool to help doctors predict serious heart and brain problems in older patients having non-heart surgeries, so they can better manage their care and improve recovery.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages65 Years and up
SexAll
SponsorBeijing Tsinghua Chang Gung Hospital Academic / other
Locations1 site (Beijing, Beijing)
Trial IDNCT06391632 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop a prediction model for major adverse cardiac and cerebrovascular events (MACCE) in elderly patients over 65 years old undergoing elective non-cardiac surgery. By enrolling approximately 3000 patients, the study will collect data before, during, and after surgery to observe the occurrence of serious complications. The goal is to enhance the predictive ability for postoperative complications, allowing for better risk assessment and management of elderly patients. Ultimately, this model aims to reduce the incidence of MACCE and improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are elderly patients aged 65 and older who are scheduled for elective non-cardiac surgery.

Not a fit: Patients undergoing local anesthesia, day surgery, or those expected to have a short hospital stay may not benefit from this study.

Why it matters

Potential benefit: If successful, this model could significantly enhance the safety and management of elderly patients undergoing elective non-cardiac surgeries.

How similar studies have performed: Other studies have shown promise in developing predictive models for postoperative complications, indicating that this approach has potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The subjects were patients with elective non-cardiac surgery;
* Older than 65 years;
* Patients signed informed consent.

Exclusion Criteria:

* The anesthesia should be received in any of the following ways: local anesthesia;
* local anesthesia enhancement, and simple nerve block anesthesia;
* Patients who are scheduled to undergo day surgery;
* Expected operation time \<1 hour for patients;
* Patients who are expected to stay in hospital for less than 3 days after surgery;
* Patients who refuse to enroll.

Where this trial is running

Beijing, Beijing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Major Adverse Cardiac EventsCerebrovascular AccidentPostoperative ComplicationsModelsElderly patientsElective non-cardiac surgeryMACCEsSelective Operation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.