Predicting the need for carpal tunnel surgery using baseline scores

Predictive Value of Baseline CTQ-SSS Scores for Progression to Carpal Tunnel Release Surgery: A Prospective Cohort Study

Ahram Canadian University · NCT05838963

This study is testing if initial scores from a symptom questionnaire can help predict which patients with carpal tunnel syndrome might need surgery in the future.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorAhram Canadian University (other)
Locations1 site (Al Ḩayy Ath Thāmin, Giza)
Trial IDNCT05838963 on ClinicalTrials.gov

What this trial studies

This observational cohort study aims to evaluate how baseline CTQ-SSS scores can predict the likelihood of patients with carpal tunnel syndrome progressing to carpal tunnel release surgery. It will involve at least 200 patients who are currently managing their symptoms non-surgically. Participants will complete the CTQ-SSS and other functional assessments at multiple time points over a year. The study will utilize logistic regression models to analyze the data while adjusting for factors like age, sex, and symptom severity.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with symptoms of carpal tunnel syndrome and a positive nerve conduction study.

Not a fit: Patients who have undergone hand or wrist surgery within the past 6 months or have severe cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify patients who may benefit from early surgical intervention, potentially improving their outcomes.

How similar studies have performed: While similar predictive studies exist, this specific approach using CTQ-SSS scores for carpal tunnel syndrome progression is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with symptoms consistent with carpal tunnel syndrome, such as numbness, tingling, or pain in the hand or wrist.
* Patients with a positive nerve conduction study confirming carpal tunnel syndrome, OR patients with clinical symptoms and signs consistent with carpal tunnel syndrome if a nerve conduction study is not available or inconclusive.
* Patients who have not undergone hand or wrist surgery within the past 6 months.
* Patients who are 18 years of age or older.
* Patients who are willing and able to provide informed consent and comply with study requirements.

Exclusion Criteria:

* Patients with a history of hand or wrist surgery within the past 6 months.
* Patients with severe hand or wrist pain that would prevent completion of the outcome measures or interfere with their ability to participate in the study.
* Patients with severe cognitive impairment or language barrier that would prevent understanding of the study instructions or interfere with their ability to participate in the study.
* Patients with other neurologic or musculoskeletal disorders that could affect hand function or interfere with test completion.
* Pregnant or breastfeeding women.
* Patients who have participated in another clinical trial within the past 30 days.

Where this trial is running

Al Ḩayy Ath Thāmin, Giza

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Carpal Tunnel Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.