Predicting successful extubation in traumatic brain injury patients
Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury Observational Study
This study is testing if measuring breathing strength can help doctors know when it's safe to take patients with traumatic brain injuries off mechanical ventilation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Benha University Academic / other |
| Locations | 1 site (Tanta, Mahala) |
| Trial ID | NCT06627686 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the predictive power of respiratory muscle strength and central drive in determining the success of weaning from mechanical ventilation in patients with traumatic brain injury. It involves measuring maximal inspiratory pressure and airway occlusion pressure before conducting spontaneous breathing trials. The study will monitor patients closely during the process to ensure accurate data collection and patient safety. The goal is to identify reliable indicators that can help clinicians make informed decisions about extubation.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 65 with closed traumatic brain injury who have been intubated and on mechanical ventilation for more than 24 hours.
Not a fit: Patients with conditions that prevent successful weaning from mechanical ventilation or those who do not meet the eligibility criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the weaning process from mechanical ventilation, potentially reducing complications and hospital stays for patients with traumatic brain injury.
How similar studies have performed: Other studies have explored similar predictive measures in mechanical ventilation weaning, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Traumatic brain injury (closed type) patients who will be admitted to ICU and intubated and MV more than 24 hours will be included in this study. Age from 18 to 65 years (male or female). Fulfillment of Criteria of readiness for weaning off MV : Resolution of the cause of respiratory insufficiency and MV. Stable hemodynamic profile
Where this trial is running
Tanta, Mahala
- Ali Rashad Ahmed — Tanta, Mahala, Egypt (Recruiting)
Study contacts
- Principal investigator: Ali Rashad, MBBCH — Benha University
- Study coordinator: Ali Rashad, MBBCH
- Email: draliali123456@gmail.com
- Phone: 201018020543
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.