Predicting psychological and physical problems after ICU discharge
Prediction of the Post-intensive Care Syndrome
This study is testing if checking in with patients when they leave the ICU can help predict if they will have mental health issues or new physical problems three months later.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 800 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Region Stockholm Government |
| Locations | 4 sites (Stockholm and 3 other locations) |
| Trial ID | NCT05690438 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate whether screening patients at the time of discharge from the intensive care unit (ICU) can effectively predict the development of psychological symptoms and new-onset physical disabilities three months later. The study will involve 800 adult patients who have spent at least 12 hours in the ICU, utilizing novel screening instruments to assess risks for post-intensive care syndrome (PICS). Participants will complete digital questionnaires to report on their mental health and physical abilities after their ICU stay, while also considering factors like pain, resilience, and frailty.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients aged 18 and older who have been discharged from the ICU after a stay of 12 hours or more.
Not a fit: Patients with significant cognitive dysfunction, such as dementia, or those who do not have a home address may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved identification and management of psychological and physical issues in ICU survivors, enhancing their recovery and quality of life.
How similar studies have performed: Other studies have shown promise in using screening methods to predict post-intensive care syndrome, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients, ≥18 years old, with an ICU stay ≥12 hours, surviving to ICU discharge. Exclusion Criteria: * No home address * Dementia or other major cognitive dysfunction * Unsufficient knowledge of the Swedish language for answering follow-up questionnaires * Two or more limitations of treatment or moribund patient
Where this trial is running
Stockholm and 3 other locations
- Karolinska University Hospital — Stockholm, Sweden (Recruiting)
- Capio S:t Göran's Hospital — Stockholm, Sweden (Recruiting)
- Danderyd's Hospital — Stockholm, Sweden (Recruiting)
- Södersjukhuset — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Anna Milton — Karolinska Institutet/Karolinska University Hospital
- Study coordinator: Anna Milton
- Email: anna.milton@regionstockholm.se
- Phone: +46812370000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.