Clinical trial No longer in our active list Observational Ages 18 to 80

Predicting lymphovascular invasion in pancreatic cancer patients before surgery

Official title: Development and Validation of a Preoperative Model to Predict the Lymphovascular Invasion of Pancreatic Ductal Adenocarcinoma: a Multicenter Retrospective Study

Run by Tianjin Medical University Cancer Institute and Hospital · NCT05997147 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is trying to create a tool that helps doctors predict if pancreatic cancer patients will have lymphovascular invasion before they have surgery, which could guide their treatment choices.

More Pancreas Cancer trials

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment1009 (estimated)
SponsorTianjin Medical University Cancer Institute and Hospital
Academic / other
Locations1 site (Tianjin, Tianjin)
Trial IDNCT05997147 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have been pathologically diagnosed with PDAC and are scheduled for curative surgery.

Probably not a fit

Patients with distant metastasis, those who have received neoadjuvant therapy, or those with a survival time of less than one month may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to develop a preoperative model to predict lymphovascular invasion (LVI) in patients diagnosed with pancreatic ductal adenocarcinoma (PDAC). By analyzing data from patients at three tertiary hospitals, the researchers will use univariate and multivariate logistic regression to identify independent predictors of LVI. A nomogram will be created based on these findings, and its predictive accuracy will be evaluated using ROC curves and calibration plots. The study seeks to provide a tool that could help guide treatment decisions for PDAC patients.

Why it matters

Potential benefit: If successful, this model could help identify patients who may benefit from neoadjuvant therapy, potentially improving their survival outcomes.

How similar studies have gone: While predictive models for cancer prognosis are common, this specific approach to predicting LVI in PDAC is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who were pathologically diagnosed as PDAC and received curative surgery.

Exclusion Criteria:

* Patients with distant metastasis; Patients who received neoadjuvant therapy; Patients with a survival time of less than 1 month.

Where it's running

  • Tianjin Medical University Cancer Institute and Hospital
    Tianjin, Tianjin, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.