Predicting language recovery in stroke patients

Predicting Language Recovery in Acute Stroke Patients in the Neurovascular Intensive Care Unit: An Exploratory Study With the Core Assessment of Language Processing.

Assistance Publique - Hôpitaux de Paris · NCT06817642

This study is testing if a new language assessment can help predict how well stroke patients will recover their language skills soon after their stroke.

Quick facts

Study typeObservational
Enrollment570 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorAssistance Publique - Hôpitaux de Paris (other)
Locations1 site (Créteil)
Trial IDNCT06817642 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate whether the Core Assessment of Language Processing (CALAP) can predict language abilities in stroke patients during their acute phase. By assessing language and cognitive abilities shortly after a stroke, the study seeks to identify patients at risk for persistent language disorders. This early identification could enhance management strategies and improve cognitive rehabilitation outcomes for affected individuals. The study focuses on patients aged 18 to 85 who are hospitalized within 21 days of experiencing a stroke.

Who should consider this trial

Good fit: Ideal candidates are Francophone stroke patients aged 18 to 85 who are hospitalized within 21 days of their stroke.

Not a fit: Patients with severe alertness impairment or those who cannot participate in cognitive assessments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies for stroke patients with language disorders.

How similar studies have performed: While the approach of predicting language recovery in stroke patients is explored, this specific methodology using CALAP is novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age: between 18 and 85 years old
* Inpatient in the initial phase of stroke (between 0 and 21 days after stroke)
* Hemispheric stroke, ischemic or haemorrhagic
* Ability to participate in tests
* Francophone
* 4≤ NIHSS score ≤21 or if NIHSS score \< 4, LAST score \[0-13\]
* Non-opposition to participation in tests

Exclusion Criteria:

* Severe alertness impairment incompatible with test participation, NIHSS score 1a. different from 0
* Severe overall intellectual deterioration incompatible with test participation
* Patients who may have a visual or hearing impairment incompatible with participation in CALAP
* History of stroke
* Posterior fossa stroke

Where this trial is running

Créteil

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke Patients, Stroke, Aphasia, Language abilities, Cognitive abilities, Prediction of function recovery

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.