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Clinical trial Recruiting at 1 site Observational Ages 18 to 85

Predicting language recovery in stroke patients

Official title: Predicting Language Recovery in Acute Stroke Patients in the Neurovascular Intensive Care Unit: An Exploratory Study With the Core Assessment of Language Processing.

Run by Assistance Publique - Hôpitaux de Paris · NCT06817642 · Data updated 2026-11-12

This study is testing if a new language assessment can help predict how well stroke patients will recover their language skills soon after their stroke.

Quick facts

Study typeObservational
Ages18 Years to 85 Years
SexAll
Enrollment570 (estimated)
SponsorAssistance Publique - Hôpitaux de Paris
Academic / other
Locations1 site (Créteil)
StatusRecruiting
StartedJanuary 1, 2023
Main results expectedJune 30, 2029
Study endsDecember 1, 2029
Registry record updatedJune 4, 2025
Trial IDNCT06817642 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Francophone stroke patients aged 18 to 85 who are hospitalized within 21 days of their stroke.

Probably not a fit

Patients with severe alertness impairment or those who cannot participate in cognitive assessments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate whether the Core Assessment of Language Processing (CALAP) can predict language abilities in stroke patients during their acute phase. By assessing language and cognitive abilities shortly after a stroke, the study seeks to identify patients at risk for persistent language disorders. This early identification could enhance management strategies and improve cognitive rehabilitation outcomes for affected individuals. The study focuses on patients aged 18 to 85 who are hospitalized within 21 days of experiencing a stroke.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies for stroke patients with language disorders.

How similar studies have gone: While the approach of predicting language recovery in stroke patients is explored, this specific methodology using CALAP is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age: between 18 and 85 years old
* Inpatient in the initial phase of stroke (between 0 and 21 days after stroke)
* Hemispheric stroke, ischemic or haemorrhagic
* Ability to participate in tests
* Francophone
* 4≤ NIHSS score ≤21 or if NIHSS score \< 4, LAST score \[0-13\]
* Non-opposition to participation in tests

Exclusion Criteria:

* Severe alertness impairment incompatible with test participation, NIHSS score 1a. different from 0
* Severe overall intellectual deterioration incompatible with test participation
* Patients who may have a visual or hearing impairment incompatible with participation in CALAP
* History of stroke
* Posterior fossa stroke

Where it's running

  • Assistance Publique Hôpitaux de Paris - Hôpital Henri Mondor
    Créteil, France     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.