Predicting inpatient rehabilitation length after hip or knee replacement
Official title: Transforming Rehabilitation: Personalised Care for a Better Quality of Life (PREPARE, Phase 2)
Run by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT07304323 · Data updated 2026-11-12
This project will try to use past hospital records to train and test a model that predicts how long adults who had hip or knee replacement for osteoarthritis will need inpatient rehabilitation.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Academic / other |
| Locations | 1 site (Milan) |
| Status | Recruiting |
| Started | October 8, 2025 |
| Main results expected | October 31, 2026 |
| Study ends | October 31, 2026 |
| Registry record updated | December 26, 2025 |
| Trial ID | NCT07304323 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) who had total hip or knee replacement for osteoarthritis at IRCCS Galeazzi in 2018 and were subsequently discharged to inpatient rehabilitation are the focus of this analysis.
✕Probably not a fit
Patients under 18, those who had other types of surgery, those treated at other hospitals, or those with incomplete clinical records are not represented and are unlikely to benefit directly from this dataset or model.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will extract retrospective clinical and surgical data from patients who underwent total hip or knee replacement at IRCCS Galeazzi and were discharged to inpatient rehabilitation in 2018. They will analyze demographic, surgical, laboratory, pain, cognitive, and functional measures (including Barthel Index and physiotherapy evaluations) to train and externally validate a predictive model for inpatient rehabilitation length of stay. The primary outcome is rehabilitation length of stay and secondary outcomes include place of discharge, burden of care at discharge, and functional recovery. No new patients will be recruited because the analysis uses existing clinical records stored in the hospital databases.
Why it matters
Potential benefit: If successful, the model could help clinicians anticipate rehabilitation needs and improve discharge planning to shorten stays and tailor post-operative support.
How similar studies have gone: Similar predictive-model approaches for length of stay after joint replacement have shown promise in prior studies, though robust external validation across centers is still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients admitted for THR and TKR at IRCCS Galeazzi Orthopedic Institute in 2018 (any month) and subsequently discharged to inpatient rehabilitation in the same structure. * Aged ≥18 years. * International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9CM) Diagnoses: 715.15, 16, 25, 26 (primary and secondary osteoarthritis of the hip and knee). * ICD-9CM Surgical procedures: 81.51, 81.54 (total joint replacement of the hip and knee). Exclusion Criteria: * Age \< 18 years (if any).
Where it's running
-
IRCCS Ospedale Galeazzi-Sant'Ambrogio
Milan, Italy Recruiting
Study contacts
- Principal investigator: Federico Pennestrì, PhD — IRCCS Ospedale Galeazzi Sant'Ambrogio
- Study coordinator: Coordinator of the Scientific Direction
- Email: direzionescientifica.ogsa@grupposandonato.it
- Phone: +39 0283502224
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.