Predicting early surgery needs in Crohn's disease using imaging data
Study of Imaginomics Predicting Early Surgical Rates in Crohn's Disease
Sixth Affiliated Hospital, Sun Yat-sen University · NCT05174208
This study is trying to see if using imaging data can help doctors predict which patients with Crohn's disease might need surgery early on.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Sixth Affiliated Hospital, Sun Yat-sen University (other) |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05174208 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with Crohn's disease (CD) to develop a digital prognostic model that predicts the risk of early surgical intervention. By utilizing radiomics from CTE examinations, the study aims to create a nomogram that can assist clinicians in identifying patients at higher risk for complications requiring surgery. The goal is to enhance therapeutic strategies and improve patient outcomes through better risk assessment. Participants will be followed for more than a year to gather comprehensive data.
Who should consider this trial
Good fit: Ideal candidates are patients with a confirmed diagnosis of Crohn's disease who have not undergone previous intestinal surgeries and have complete CTE data.
Not a fit: Patients who have had previous intestinal surgeries or those without a confirmed diagnosis of Crohn's disease will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a valuable tool for predicting surgical needs in Crohn's disease patients, leading to timely interventions and improved management.
How similar studies have performed: While the use of radiomics in predicting surgical outcomes is an emerging field, similar studies have shown promise in other conditions, suggesting potential success for this approach in Crohn's disease.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: patients with a confirmed diagnosis of CD; a follow-up more than 1 year; without previous CD-associated intestinal surgeries; complete data of CTE. Exclusion Criteria: patients without a confirmed diagnosis of CD; with incomplete data and a follow-up less than 1 year; patients have previous intestinal surgeries; patients who have never undergone CTE examination.
Where this trial is running
Guangzhou, Guangdong
- the Sixth Affiliated Hospital of Sun Yat-Sen University — Guangzhou, Guangdong, China (RECRUITING)
Study contacts
- Study coordinator: Jiayin Yao, Professor
- Email: yjyin@mail3.sysu.edu.cn
- Phone: 13826462890
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Crohn Disease, Prognostic Model, Radiomics