Pre-treatment rehabilitation program for cancer patients

Cancer Survival and Outcomes Impact of Universal Disability Screening and Cancer Rehabilitation Referral Among Adults With Cancer Referred to the University of North Carolina

Not applicable Interventional UNC Lineberger Comprehensive Cancer Center · NCT06674889

This study is testing whether a special exercise and support program before cancer treatment can help high-risk patients feel better and have improved results during their care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUNC Lineberger Comprehensive Cancer Center Academic / other
Locations1 site (Chapel Hill, North Carolina)
Trial IDNCT06674889 on ClinicalTrials.gov

What this trial studies

This pilot health services interventional study aims to evaluate the effectiveness of a pre-treatment rehabilitation program for adult cancer patients identified as high-risk. Patients will be screened and referred to participate in tailored prehabilitation interventions, with the study tracking functional outcomes and quality of life. The goal is to demonstrate the benefits of prehabilitation on the cancer treatment continuum, hypothesizing that those in the intervention group will experience better outcomes compared to those who do not receive the intervention.

Who should consider this trial

Good fit: Ideal candidates are adult cancer patients aged 18 and older who have been screened and referred to oncology clinics with high-risk features.

Not a fit: Patients who are unable to provide informed consent or have unstable medical comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve the functional outcomes and quality of life for cancer patients undergoing treatment.

How similar studies have performed: Other studies have shown promising results with prehabilitation approaches in cancer care, indicating potential for success in this intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Written informed consent obtained to participate in the study and HIPAA authorization for the release of personal health information.
* Subjects are willing and able to comply with study procedures based on the judgement of the investigator.
* Age ≥ 18 years at the time of consent.
* The subject has been screened by the Central Oncology Navigation Program and referred to cancer care at the University of North Carolina Medical Center.
* Answer "yes" to at least one of the following screening questions:

  1. Does your health interfere with any of your activities of daily living (ADLs)?
  2. Have you fallen, or do you feel unsteady while standing or walking?
  3. Do you use durable medical equipment (DME)?
  4. Are you interested in increasing the amount you exercise?

Exclusion Criteria:

* Inability to read and understand the English language.
* Psychological or other disability resulting in the inability to provide informed consent.
* Unstable medical comorbidity that precludes safe participation in an exercise program, in the judgment of the clinical investigator.
* Prisoners and other institutionalized individuals.

Where this trial is running

Chapel Hill, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerMalignant Tumorrehabilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.