Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Pre-surgery nutrition and inflammation markers and early recovery after sleeve gastrectomy

Official title: The Relationship Between Preoperative Nutritional and Inflammatory Markers and Early Postoperative Clinical Outcomes in Patients Undergoing Bariatric Surgery

Run by Istinye University · NCT07007494 · Data updated 2026-11-12

This project tests whether pre-surgery nutrition and inflammation lab markers (PNI, HALP, NLR, CRP) can help predict early recovery, complications, and hospital stay length in adults having elective laparoscopic sleeve gastrectomy.

More Postoperative Complications trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment86 (estimated)
SponsorIstinye University
Academic / other
Locations1 site (Istanbul, Merkez Mahallesi)
StatusRecruiting
StartedJune 2, 2025
Main results expectedAugust 2, 2025
Study endsAugust 15, 2025
Registry record updatedJuly 16, 2025
Trial IDNCT07007494 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 with BMI ≥35 kg/m² who are scheduled for elective laparoscopic sleeve gastrectomy and have complete preoperative lab results are ideal candidates.

Probably not a fit

Patients with severe liver or kidney failure, active infection, hematologic malignancies, recent immunosuppression, or those requiring ICU within 72 hours are unlikely to benefit from these marker-based predictions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling adults with BMI ≥35 who are scheduled for elective laparoscopic sleeve gastrectomy at Istinye University in Istanbul. Investigators will collect preoperative laboratory data to calculate PNI, HALP score, NLR, and CRP and then track early postoperative outcomes including time to oral intake, mobilization, complications, and length of hospital stay. Key exclusions include severe hepatic or renal dysfunction, active infection, history of immunosuppressive therapy or hematologic malignancy, perioperative albumin or blood product use, and need for ICU admission within the first 72 hours. Associations between preoperative marker levels and early clinical outcomes will be analyzed using regression models and predictive performance metrics.

Why it matters

Potential benefit: If successful, this could help clinicians identify patients at higher risk for delayed recovery or complications before surgery so they can tailor perioperative care.

How similar studies have gone: Similar biomarker approaches (PNI, NLR, CRP) have shown associations with outcomes in other surgical populations, but their predictive value specifically for sleeve gastrectomy is not yet well established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 65 years
* Body mass index (BMI) ≥ 35 kg/m²
* Scheduled for elective laparoscopic sleeve gastrectomy
* Availability of complete preoperative laboratory test results
* Signed informed consent

Exclusion Criteria:

* Severe hepatic or renal dysfunction
* Presence of active infection
* History of immunosuppressive therapy or hematologic malignancy
* Need for intensive care unit (ICU) admission within the first 72 hours postoperatively
* Preoperative administration of albumin or blood products

Where it's running

  • Istinye Üniversity
    Istanbul, Merkez Mahallesi, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.