Povidone-iodine versus chlorhexidine wound wash after total hip replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults scheduled for primary total hip replacement for hip osteoarthritis or avascular necrosis will be randomly assigned to wound irrigation with either povidone-iodine or chlorhexidine at the time of wound closure. All other aspects of the operation and postoperative care will follow standard practice. Incision photographs will be taken at two and six weeks and reviewed using a standardized method, and electronic medical records will be checked for postoperative complications, readmissions, or additional surgeries. Patients with known allergy to either antiseptic are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* osteoarthritis or avascular necrosis of the femoral head, failed conservative management, indicated for total hip replacement

Exclusion Criteria:

* reported or documented allergy to chlorhexidine or povidone-iodine

Where it's running

• UPMC East
  Monroeville, Pennsylvania, United States Recruiting
• UPMC Shadyside
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Frank J Plate, MD, PhD — University of Pittsburgh
• Study coordinator: Frank J Plate, MD, PhD
• Email: platefj2@upmc.edu
• Phone: (412) 687-3900

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.