Postpartum Mom Power for Opioid Use Disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a two-site randomized trial enrolling about 80 mothers per group to evaluate a maternal postpartum intervention called Mom Power (vMP) for those with opioid use disorder. Participants are assessed before and after the program with behavioral measures and brain imaging to explore changes in maternal brain networks, stress, mood, and cravings. The study compares vMP to enhanced usual care and examines whether brain and behavioral changes mediate any clinical benefits. Eligibility includes OUD diagnosis or MAT, a child aged 5 or younger, and English proficiency; MRI safety criteria apply. The trial is led by Stony Brook University with collaboration from the University of Michigan.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* mothers with diagnosis of Opioid Use Disorder (OUD); and/or receiving medication assisted treatment (such as buprenorphine or methadone)
* with a child aged 5 or less
* able to read, hear and understand English adequately enough to provide informed consent

Exclusion Criteria:

* require immediate clinical care for suicidal/homicidal risk or psychosis;
* For magnetic resonance imaging (MRI) of the brain, potential participants will be excluded if they: (1) have ferromagnetic metal in their heads (2) have severe claustrophobia that prevents participation in the neuroimaging (3) have serious neurological condition that could interfere with neuroimaging, including a brain tumor, multiple sclerosis or significant head trauma

Where it's running

• University of Michigan
  Ann Arbor, Michigan, United States Recruiting
• Stony Brook University
  Stony Brook, New York, United States Recruiting

Study contacts

• Principal investigator: James E Swain, MD, PhD — Stony Brook University
• Study coordinator: James E Swain, MD, PhD
• Email: james.swain@stonybrookmedicine.edu
• Phone: 516-838-7604

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.