Post-stroke fatigue and related clinical factors
Official title: Frequency of Post-stroke Fatigue and Its Relationship With Clinical Parameters
Run by Ankara University · NCT07231172 · Data updated 2026-11-12
We will try to find how common fatigue is and which health and personal factors are linked to it in adults at least three months after their first stroke.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 107 (estimated) |
| Sponsor | Ankara University Academic / other |
| Locations | 1 site (Ankara) |
| Status | Recruiting |
| Started | November 21, 2024 |
| Main results expected | January 29, 2026 |
| Study ends | January 29, 2026 |
| Registry record updated | November 17, 2025 |
| Trial ID | NCT07231172 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with a first-ever stroke at least three months earlier, confirmed by CT/MRI, who can follow commands (MMSE ≥24), can walk at least to FAC stage 2, and can attend clinic visits are ideal candidates.
✕Probably not a fit
People with prior strokes, significant aphasia or dementia, active severe medical illnesses that cause fatigue, illiteracy, or who are less than three months post-stroke are unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will recruit adults with a first-ever stroke confirmed by CT or MRI who are at least three months post-stroke and able to ambulate (Functional Ambulation Classification ≥2). Fatigue prevalence will be measured using validated tools such as the Fatigue Severity Scale and a Visual Analog Scale for fatigue, while researchers collect data on demographics, stroke type and duration, pain, mood, sleep, motor and cognitive status, spasticity, physical endurance, ambulation, independence in daily activities, and health-related quality of life. Patients with previous strokes, significant cognitive or communication impairments, illiteracy, or medical conditions that independently cause fatigue are excluded. The study is conducted at Ankara University and will use these clinical correlations to describe frequency and associated factors of post-stroke fatigue in this patient population.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify patients at higher risk of long-lasting fatigue after stroke and guide more targeted rehabilitation and support.
How similar studies have gone: Previous observational studies have reported high prevalence of post-stroke fatigue (roughly 39–68%) and have linked fatigue to mood, sleep, and motor impairments, so this work builds on established findings while providing local clinic data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being diagnosed with stroke according to definition by the World Health Organization * Being over 18 years of age * Having had a stroke confirmed by Computed Tomography (CT) and/or Magnetic Resonance Imaging (MRI) * At least 3 months after stroke * At least stage 2 according to the Functional Ambulation Classification * Agreed to participate in the study and signed the informed consent form Exclusion Criteria: * Previous history of stroke * Communication problems due to reasons such as aphasia and dementia * Patients who are illiterate * Cognitive functional impairment who cannot take commands (MMSE\<24) * Dİagnoses such as cancer, heart failure, liver failure, renal failure that may cause fatigue * Signs of systemic infection * History of subarachnoid hemorrhage
Where it's running
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Ankara University
Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Ayşe A. Küçükdeveci, Prof — Ankara University
- Study coordinator: Mehmet Tekeş, MD
- Email: yusuf1tekes@gmail.com
- Phone: +903125082822
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
-
Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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Nutrition's impact on fatigue after stroke
This study is testing if a nutritional supplement can help stroke survivors feel less tired and improve their overall well-being.
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Magnetic stimulation treatment for fatigue after stroke
This study is testing whether a type of magnetic treatment can help stroke survivors feel less tired and improve their overall well-being.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.