Post-stroke fatigue and related clinical factors
Frequency of Post-stroke Fatigue and Its Relationship With Clinical Parameters
We will try to find how common fatigue is and which health and personal factors are linked to it in adults at least three months after their first stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 107 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ankara University Academic / other |
| Locations | 1 site (Ankara) |
| Trial ID | NCT07231172 on ClinicalTrials.gov |
What this trial studies
This observational study will recruit adults with a first-ever stroke confirmed by CT or MRI who are at least three months post-stroke and able to ambulate (Functional Ambulation Classification ≥2). Fatigue prevalence will be measured using validated tools such as the Fatigue Severity Scale and a Visual Analog Scale for fatigue, while researchers collect data on demographics, stroke type and duration, pain, mood, sleep, motor and cognitive status, spasticity, physical endurance, ambulation, independence in daily activities, and health-related quality of life. Patients with previous strokes, significant cognitive or communication impairments, illiteracy, or medical conditions that independently cause fatigue are excluded. The study is conducted at Ankara University and will use these clinical correlations to describe frequency and associated factors of post-stroke fatigue in this patient population.
Who should consider this trial
Good fit: Adults over 18 with a first-ever stroke at least three months earlier, confirmed by CT/MRI, who can follow commands (MMSE ≥24), can walk at least to FAC stage 2, and can attend clinic visits are ideal candidates.
Not a fit: People with prior strokes, significant aphasia or dementia, active severe medical illnesses that cause fatigue, illiteracy, or who are less than three months post-stroke are unlikely to benefit from this study's findings.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify patients at higher risk of long-lasting fatigue after stroke and guide more targeted rehabilitation and support.
How similar studies have performed: Previous observational studies have reported high prevalence of post-stroke fatigue (roughly 39–68%) and have linked fatigue to mood, sleep, and motor impairments, so this work builds on established findings while providing local clinic data.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being diagnosed with stroke according to definition by the World Health Organization * Being over 18 years of age * Having had a stroke confirmed by Computed Tomography (CT) and/or Magnetic Resonance Imaging (MRI) * At least 3 months after stroke * At least stage 2 according to the Functional Ambulation Classification * Agreed to participate in the study and signed the informed consent form Exclusion Criteria: * Previous history of stroke * Communication problems due to reasons such as aphasia and dementia * Patients who are illiterate * Cognitive functional impairment who cannot take commands (MMSE\<24) * Dİagnoses such as cancer, heart failure, liver failure, renal failure that may cause fatigue * Signs of systemic infection * History of subarachnoid hemorrhage
Where this trial is running
Ankara
- Ankara University — Ankara, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Ayşe A. Küçükdeveci, Prof — Ankara University
- Study coordinator: Mehmet Tekeş, MD
- Email: yusuf1tekes@gmail.com
- Phone: +903125082822
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.