Post-authorization registry of people treated with LEQEMBI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a noninterventional, prospective observational registry. It collects real-world safety data on LEQEMBI, including ARIA-E, ARIA-H, and intracerebral hemorrhage events, and compares incidence by APOE4 status, use of antithrombotics, and baseline MRI findings. Data will be summarized overall and by these subgroups to understand long-term safety in routine practice. The study also aims to describe progression to later stages of Alzheimer's disease and to identify previously unknown adverse events not seen in earlier trials. Enrollment is limited to individuals in Canada who are prescribed LEQEMBI, with no study interventions beyond observation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants with Alzheimer's Disease who are prescribed LEQEMBI in Canada.

Exclusion Criteria:

* None

Where it's running

• Kawartha Center
  Peterborough, Ontario, Canada Recruiting
• Toronto Memory Program
  Toronto, Ontario, Canada Recruiting
• Moca
  Greenfield Park, Quebec, Canada Recruiting
• University of Calgary - Hotchkiss Brain Institute
  Calgary, Alberta, Canada Not yet recruiting
• University of Alberta, Geriatric Division
  Edmonton, Alberta, Canada Not yet recruiting
• University of British Columbia - CARD
  Vancouver, British Columbia, Canada Not yet recruiting

Study contacts

• Study coordinator: Eisai Medical Information
• Email: esi_medinfo@eisai.com
• Phone: +1-888-274-2378

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.