Portable Rehabilitation Interface (PoRI) for improving hand function after stroke
Randomized Clinical Trial of (PoRI) Post-Stroke Hand Rehabilitation Device
This trial tests the PoRI portable hand-rehabilitation device to see if it helps people who recently had a stroke regain hand motor function compared with standard hand therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 12 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Yale University Academic / other |
| Locations | 1 site (Milford, Connecticut) |
| Trial ID | NCT07407023 on ClinicalTrials.gov |
What this trial studies
This is a randomized, controlled trial comparing a portable device-based therapy (PoRI) with conventional hand therapy in patients early after stroke. Participants are enrolled between 2 days and 2 months after their stroke and have reduced hand strength (0–3/5) or sensorimotor finger problems. The device must comfortably fit the participant's hand and allow passive range of motion to neutral; those who cannot meet those requirements are excluded. Treatments are delivered in Yale New Haven Hospital's Inpatient Rehabilitation Unit (Milford, CT) and outcomes focus on hand motor recovery and functional use.
Who should consider this trial
Good fit: Ideal candidates are people 2 days to 2 months after a stroke with significant hand weakness (0–3/5) or sensorimotor finger impairment who can fit their hand into the device and tolerate passive range of motion exercises.
Not a fit: Patients more than 2 months or less than 2 days after stroke, those with near-normal hand strength (4–5/5), those who cannot achieve neutral passive wrist/finger positioning, or vulnerable populations are unlikely to benefit from this trial.
Why it matters
Potential benefit: If successful, PoRI could speed and improve hand motor recovery after stroke, leading to better hand function and reduced disability.
How similar studies have performed: Other robotic and device-assisted hand rehabilitation approaches have shown promise in improving post-stroke hand function, but PoRI is a specific portable interface being tested in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between 2 days and a maximum of 2 months have passed since the stroke event * 0-3/5 muscle strength * Participants with paralysis or sensorimotor function problems of the fingers of one or both hands. * Participants must be able to fit their hand comfortably into the device. Exclusion Criteria: * Less than 2 days or greater than 2 months have passed since the stroke event * 4-5/5 muscle strength * Vulnerable populations. * Inability of fingers and wrist to stretch to neutral during passive range of motion
Where this trial is running
Milford, Connecticut
- Yale New Haven Hospital's Inpatient Rehabilitation Unit — Milford, Connecticut, United States (Recruiting)
Study contacts
- Principal investigator: Necolle Morgado-Vega — Yale University
- Study coordinator: Necolle Morgado-Vega
- Email: necolle.morgado-vega@yale.edu
- Phone: 203-843-5733
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.