Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Popliteal Vein Size After Long-Distance Air Travel Before Plastic Surgery

Official title: Prospective Repeated-Measures Study of Popliteal Vein Diameter During the First 48 Hours After Commercial Air Travel to Bogota for a Plastic Surgery Intervention

Run by Research Inc · NCT07808411 · Data updated 2026-11-12

We will test whether the popliteal vein stays enlarged after international air travel to Bogota, by doing ultrasound checks before travel and at 2, 24, and 48 hours after arrival.

More Physiologic Venous Dilation trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment100 (estimated)
SponsorResearch Inc
Industry-sponsored
Locations1 site (Bogotá)
StatusRecruiting
StartedJanuary 12, 2024
Main results expectedSeptember 1, 2026
Study endsDecember 1, 2026
Registry record updatedSeptember 8, 2026
Trial IDNCT07808411 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–65 traveling internationally to Bogota for a plastic surgery procedure who can undergo ultrasound exams at the specified times.

Probably not a fit

Patients with recent leg surgery, active venous disease, or inability to complete all ultrasounds may not benefit from the findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study will measure how the popliteal vein diameter changes over the first 48 hours after an international flight to Bogota. Adults traveling for medical reasons will have standardized bilateral popliteal vein ultrasounds 24 hours before departure, within 2 hours after arrival, and at 24 and 48 hours post-arrival, all before any surgery or IV fluids. A fixed resting protocol and triplicate measurements will be used, and factors like flight duration, seating, movement, and fluid intake will be recorded. Mixed-effects analysis will estimate the trajectory of diameter and surface area, including the proportion returning to within 10% of baseline by 48 hours.

Why it matters

Potential benefit: If successful, the study could clarify how long venous dilation persists after travel and inform post-travel care for patients undergoing surgery.

How similar studies have gone: Prior research has described venous changes after travel, but this study uses a repeated-measures design to map the time course in a surgical-prep context, which is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 to 65 years.
* International commercial flight to Bogota with total airborne time of at least 4 hours.
* Preflight baseline ultrasound obtained within 24 hours before departure using the standardized protocol.
* Arrival ultrasound completed within 2 hours after reaching the study site and before surgery or intravenous fluid therapy.
* Availability for 24-hour and 48-hour examinations.
* Written informed consent.

Exclusion Criteria:

* Known current deep venous thrombosis or pulmonary embolism.
* Therapeutic anticoagulation at enrollment.
* Major lower-extremity venous surgery, active leg infection, or condition preventing popliteal ultrasound.
* Surgery, prolonged immobilization, or substantial intravenous fluid administration before completion of the 48-hour measurement.
* Pregnancy.
* Nondiagnostic baseline examination or inability to reproduce the landmark.

Where it's running

  • Clinica INO
    Bogotá, Colombia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.