Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Moderate knee-high compression stockings for reducing popliteal vein dilation during long-haul flights after cosmetic surgery

Official title: Randomized Assessor-Masked Trial of Moderate Graduated Compression Stockings for Popliteal Vein Dilation During Long-Haul Economy-Class Air Travel After Aesthetic Surgery

Run by Research Inc · NCT07810192 · Data updated 2026-11-12

This study tests whether wearing knee-high compression stockings during a long flight can prevent dilation of the popliteal vein after cosmetic surgery.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment160 (estimated)
SponsorResearch Inc
Industry-sponsored
Locations1 site (Bogotá)
StatusRecruiting
StartedJanuary 1, 2024
Main results expectedSeptember 1, 2026
Study endsDecember 1, 2026
Registry record updatedSeptember 9, 2026
Trial IDNCT07810192 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 traveling economy-class for at least 4 hours to Bogota after aesthetic surgery, without medical contraindications to compression.

Probably not a fit

Patients with contraindications to compression stockings or those not adherent to the study protocol may see no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, assessor-masked trial compares wearing knee-high graduated compression stockings versus no stockings in adults undergoing long-haul economy-class travel to Bogota after aesthetic surgery. Participants are assigned before departure and receive standardized preflight and postarrival duplex ultrasounds to measure popliteal vein diameter and cross-sectional area at baseline, arrival, 24 hours, and 48 hours. An intention-to-treat analysis with mixed models will estimate immediate and persistent effects of compression on venous dilation, while also recording adherence, movement, hydration, symptoms, and skin effects. The study uses enoxaparin, stockings, and standardized ultrasound protocols to assess whether compression reduces venous dilation during air travel in this setting.

Why it matters

Potential benefit: If successful, wearing compression stockings could reduce venous dilation and related discomfort or risk during long flights after cosmetic procedures.

How similar studies have gone: Prior similar approaches with compression have shown venous benefits in travel-related settings, though this exact post-surgical, assessor-masked design is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 to 65 years.
* Economy-class commercial itinerary to Bogota with at least 4 hours of total airborne time.
* No clinical indication that mandates or prohibits compression stockings.
* Ability to obtain the assigned stocking before boarding and wear it as instructed.
* Standardized preflight and postarrival ultrasounds completed before surgery.
* Written informed consent.

Exclusion Criteria:

* Current deep venous thrombosis, therapeutic anticoagulation, or severe peripheral arterial disease.
* Significant lower-limb skin disease, ulceration, neuropathy, or deformity preventing safe stocking use.
* Pregnancy.
* Planned use of another compression device during the flight.
* Surgery or major intravenous fluid therapy before completion of the 48-hour examination.
* Inability to complete preflight ultrasound or follow assigned treatment.

Where it's running

  • Clinica INO
    Bogotá, Colombia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.