Poland registry of procedures to open completely blocked coronary arteries (chronic total occlusions)
Polish Registry of Percutaneous Coronary Intervention for Chronic Total Occlusions (POL-CTO Registry)
This project will see how well and how safely percutaneous coronary intervention (PCI) works for people in Poland who are having procedures to open chronic total coronary occlusions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | National Institute of Cardiology, Warsaw, Poland Academic / other |
| Locations | 21 sites (Bialystok and 20 other locations) |
| Trial ID | NCT07330622 on ClinicalTrials.gov |
What this trial studies
This is a prospective, national multicenter registry enrolling adults undergoing CTO PCI as part of routine care at participating Polish hospitals. Investigators will collect detailed clinical, procedural, intravascular imaging, biomarker, and follow-up data to measure procedural success, periprocedural complications, and longer-term outcomes. The registry will compare different procedural strategies and devices (for example intravascular imaging use, drug-coated balloons, drug-eluting stents, hybrid techniques) and will examine the safety of PCI performed with mechanical circulatory support. Artificial intelligence–based analyses will be applied to the collected data to try to predict clinical outcomes and patient-reported quality-of-life after CTO PCI.
Who should consider this trial
Good fit: Adult patients in Poland who are undergoing PCI for a chronic total coronary occlusion and who agree to participate are the intended candidates for enrollment.
Not a fit: People who are not undergoing CTO PCI, are under 18 years old, or decline participation are unlikely to receive any direct benefit from this registry.
Why it matters
Potential benefit: If successful, the registry could identify safer and more effective CTO PCI approaches and help tailor treatment choices to improve patient outcomes and quality of life.
How similar studies have performed: International CTO registries and cohort studies have previously improved understanding of procedural success and complications with modern techniques, while the use of AI for outcome prediction remains exploratory but promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing CTO PCI based on clinical grounds Exclusion Criteria: * Age \<18 years * Patient's refusal to participate in the registry
Where this trial is running
Bialystok and 20 other locations
- Medical University of Białystok — Bialystok, Poland (Recruiting)
- Szpital Zachodni — Grodzisk Mazowiecki, Poland (Recruiting)
- Specialist Hospital in Inowrocław — Inowrocław, Poland (Recruiting)
- Medical University of Silesia — Katowice, Poland (Recruiting)
- Institute of Cardiology — Krakow, Poland (Recruiting)
- St. John Paul II Hospital — Krakow, Poland (Recruiting)
- Copper Health Centre Inc. — Lubin, Poland (Recruiting)
- 1st Military Clinical Hospital — Lublin, Poland (Recruiting)
- Hospital of the Ministry of the Interior and Administration — Lublin, Poland (Recruiting)
- University of Applied Science in Nowy Sącz — Nowy Sącz, Poland (Recruiting)
- Masovian Specialist Hospital — Ostrołęka, Poland (Recruiting)
- Poznań University of Medical Sciences — Poznan, Poland (Recruiting)
- Samodzielny Publiczny Zakład Opieki Zdrowotnej w Puławach — Puławy, Poland (Recruiting)
- Specialistic Hospital — Radom, Poland (Recruiting)
- The Ministry of Internal Affairs and Administration Hospital — Rzeszów, Poland (Recruiting)
- Military Institute of Medicine - National Research Institute — Warsaw, Poland (Recruiting)
- National Institute of Cardiology — Warsaw, Poland (Recruiting)
- The Doctor Sokolowski Hospital — Wałbrzych, Poland (Recruiting)
- Military Hospital in Wrocław — Wroclaw, Poland (Recruiting)
- University Hospital in Wroclaw — Wroclaw, Poland (Recruiting)
- Provincial Hospital in Łomża — Łomża, Poland (Recruiting)
Study contacts
- Study coordinator: Maksymilian Opolski, MD, PhD
- Email: mopolski@ikard.pl
- Phone: 0048223434127
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.