Platelets and plasma lipids as markers and targets in thrombosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational case-control study has volunteers act as their own controls to explore how different lipid emulsions affect platelet aggregation using light-transmission aggregometry with collagen, ADP, and arachidonic acid. It will measure lipid profiles and look for correlations with aggregation to understand potential biomarker links between plasma lipids and thrombosis risk. Participants must be adults without known atherosclerotic disease, not currently on antiplatelet, anticoagulant, lipid-lowering, or glucose-lowering therapies, and must fast before blood draws. The lead sponsor is the University of Sao Paulo, with study activities conducted at InCor/HCFMUSP in São Paulo, Brazil.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men and women aged ≥ 40 years.
* Willingness to sign the informed consent form.
* Absence of known atherosclerotic disease

Exclusion Criteria:

* Use of antiplatelet agents.
* Use of anticoagulants.
* Use of lipid-lowering agents.
* Use of oral hypoglycemic agents or insulin.
* Known atherosclerotic disease.
* Refusal to sign the informed consent form

Where it's running

• Heart Institute, University of São Paulo Medical School (InCor/HCFMUSP)
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: José C Nicolau, Senior Professor
• Email: jose.nicolau@fm.hc.usp.br
• Phone: 11971514117

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.