Plant-based diet for kidney transplant recipients
Effect of Plant-based Diet on Cardiometabolic and Inflammatory Parameters in Kidney Transplant Recipients
This study is testing whether a plant-based diet can improve health for people who have received a kidney transplant.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | George Washington University Academic / other |
| Locations | 1 site (Washington, District of Columbia) |
| Trial ID | NCT06186843 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effects of a plant-based diet (PBD) on kidney transplant recipients by assessing cardiometabolic and inflammatory parameters. Participants will undergo a two-week dietary training program followed by a 16-week intervention where they will consume a PBD under supervision. The study will involve regular monitoring through blood draws, urine samples, and questionnaires to track health outcomes and dietary adherence. The goal is to determine the feasibility and impact of transitioning to a PBD for improving health in this population.
Who should consider this trial
Good fit: Ideal candidates are kidney transplant recipients who are more than three months post-transplant and are currently on immunosuppressive medication.
Not a fit: Patients with active infections, advanced heart failure, or those currently following a plant-based diet may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve health outcomes and quality of life for kidney transplant recipients.
How similar studies have performed: While the specific approach of a plant-based diet for kidney transplant recipients is novel, similar dietary interventions have shown promise in improving health outcomes in other populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 3 months post-kidney transplant * On style immunosuppressive medication * Without evidence of active infection/ inflammatory conditions * Estimated glomerular filtration rate \> 45ml/min/1.73 m\^2 * English speaking * Reliable internet access Exclusion Criteria: * Acute/ chronic allograft rejection * History of non-compliance * Advance heart failure * Liver disease * Pregnancy * Malignancy * Chronic Infection * Currently following a plant-based diet
Where this trial is running
Washington, District of Columbia
- Transplant Institute — Washington, District of Columbia, United States (Recruiting)
Study contacts
- Principal investigator: Muralidharan Jagadeesan, MD — George Washington University
- Study coordinator: Muralidharan Jagadeesan, MD
- Email: mjagadeesan@mfa.gwu.edu
- Phone: 202-741-2283
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.