Pipeline Flex with Shield flow-diverter for wide‑neck intracranial aneurysms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional, prospective program uses the Pipeline Flex Embolization Device with Shield Technology as an endovascular flow‑diversion treatment for adults aged 22 and older with defined wide‑neck intracranial aneurysms. Eligible patients will undergo device implantation by a neurointerventionalist and return for scheduled imaging and clinical follow‑up to document aneurysm occlusion and safety outcomes. The Shield surface treatment is intended to reduce device thrombogenicity compared with earlier devices, and the study will collect real‑world data on technical success, occlusion rates, and adverse events. Outcomes will help clarify performance across the specified aneurysm sizes, morphologies, and parent vessel diameters.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (22 years of age or older) with large or giant wide-necked intracranial aneurysms (IAs) in the internal carotid artery from the petrous to the superior hypophyseal segments.

Exclusion Criteria:

Exclusion Criteria:

* Cannot provide consent or legally authorized representative not available to provide consent Criteria:

Where it's running

• Jacobs Institute
  Buffalo, New York, United States Recruiting

Study contacts

• Study coordinator: Carlos Pena, PhD, MS
• Email: cpena@jacobsinstitute.org
• Phone: 2404810824

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.