Photoacoustic and multispectral imaging to monitor foot wounds after surgery
Photoacoustic Imaging in Wound Evaluation and Treatment Guidance
This pilot will test whether photoacoustic and multispectral imaging can monitor blood flow and help guide care for adults with chronic foot ulcers from poor arterial circulation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | State University of New York at Buffalo Academic / other |
| Locations | 1 site (Buffalo, New York) |
| Trial ID | NCT07216599 on ClinicalTrials.gov |
What this trial studies
This pilot device study uses photoacoustic imaging alongside multispectral (Kent) imaging to measure tissue perfusion in post-surgical foot wounds. Wound care decisions in enrolled patients will be guided by the imaging results, although neither technique is currently standard clinical care. The study aims to test feasibility, identify practical issues, and collect data on drop-off rates and variation in wound healing to inform larger trials. Data collected will help determine how well these imaging methods track perfusion changes and support clinical use.
Who should consider this trial
Good fit: Adults with a chronic foot wound presumed to be caused by arterial insufficiency who can give informed consent and follow study procedures are the ideal candidates.
Not a fit: Patients with massive deep tissue infections, preexisting nearby skin conditions (e.g., melanoma or psoriasis), pregnant women, or adults unable to consent are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, these imaging methods could help clinicians detect poor tissue perfusion earlier and tailor post-surgical wound care to improve healing and reduce complications.
How similar studies have performed: Photoacoustic and multispectral imaging are emerging techniques with early preclinical and pilot clinical reports showing promise for assessing tissue perfusion, but they are not yet established as standard care.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a chronic wound on the foot that is presumed to be due to arterial insufficiency. Exclusion Criteria: * Patients with a massive deep tissue infection. * Patients with preexisting skin conditions, such as melanoma, psoriasis, in areas close to the wound(s). * Noncompliant patients who do not adhere to care plans. * Pregnant women. * Adults unable to consent.
Where this trial is running
Buffalo, New York
- UBMD Vascular Surgery — Buffalo, New York, United States (Recruiting)
Study contacts
- Study coordinator: Jun Xia, Ph.D.
- Email: junxia@buffalo.edu
- Phone: 716-645-8628
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.