Personalized treatment approach for colorectal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to establish a reliable method for personalized drug testing using fresh tumor samples from colorectal cancer patients. Investigators will develop a predictive biomarker for immunotherapy response by testing combinations of chemotherapies and CAR T cells on patient-derived organoids. The primary objective is to provide a methodology for drug screening that can identify effective therapies tailored to individual patients, while the secondary objective explores how pre-treatment with cytotoxic agents can enhance immunotherapy efficacy against solid tumors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Histologically confirmed colorectal cancer scheduled for curative surgery and standard clinical follow-up.

Exclusion Criteria:

\- Unable/unwilling to sign the informed consent form.

Where it's running

• Akershus University Hospital
  Lørenskog, Akershus, Norway Recruiting

Study contacts

• Principal investigator: Sebastian Meltzer, M.D., Ph.D. — University Hospital, Akershus
• Study coordinator: Sebastian Meltzer, M.D. Ph.D.
• Email: sebastian.meltzer@medisin.uio.no
• Phone: +4767960000

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.