Personalized robotic rehabilitation for stroke survivors
Longitudinal Study of Biomarkers for Personalized Post-Stroke Rehabilitation
This study is testing how personalized robotic therapy can help stroke survivors recover by looking at their brain activity and how it relates to their healing process.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Azienda Ospedaliero, Universitaria Pisana Academic / other |
| Locations | 1 site (Pisa, Pi) |
| Trial ID | NCT06312540 on ClinicalTrials.gov |
What this trial studies
This clinical study aims to enhance understanding of the neurophysiological mechanisms involved in recovery after a stroke. It will enroll consecutive stroke patients to collect data on various factors such as age, stroke type, and clinical outcomes over time. The study focuses on analyzing neural activity and connectivity to better understand motor deficits and recovery processes. The information gathered will help develop customized rehabilitation protocols for stroke survivors.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who have experienced a unilateral motor deficit due to a recent stroke.
Not a fit: Patients with severe cognitive impairment, psychiatric comorbidities, or end-stage organic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective personalized rehabilitation strategies for stroke survivors, improving their recovery outcomes.
How similar studies have performed: Other studies have shown promise in using neurophysiological data to guide rehabilitation, suggesting that this approach could be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * unilateral motor deficit (with or without other stroke- related symptoms or signs) * radiological evidence of unilateral, supratentorial cerebral ischemic lesion (or lesions) in the same arterial territory * stroke occurred in the last 4 days * absent or slight disability before stroke estimated by a modified Rankin Scale 0-2 Exclusion Criteria: * history of severe cognitive impairment * psychiatric comorbidities * end-stage organic diseases like cardiopulmonary, hepatic, renal failure, neoplasms, and whatever condition that could strongly reduce life expectation
Where this trial is running
Pisa, Pi
- AOUPisana — Pisa, Pi, Italy (Recruiting)
Study contacts
- Principal investigator: Carmelo Chisari, Medical — Azienda Ospedaliero, Universitaria Pisana
- Study coordinator: Carmelo Chisari, Medical
- Email: carmelo.chisari@unipi.it
- Phone: 001 050996907
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.