Personalized One Anastomosis Gastric Bypass for Weight Loss
Official title: Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial
Run by Tel-Aviv Sourasky Medical Center · NCT06829381 · Data updated 2026-11-12
This study is testing if customizing the length of a part of the stomach surgery can help adults lose more weight and improve their health compared to the standard length used in the procedure.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Tel-Aviv Sourasky Medical Center Government |
| Locations | 1 site (Tel Aviv) |
| Status | Recruiting |
| Started | January 29, 2025 |
| Main results expected | January 31, 2029 |
| Study ends | January 31, 2029 |
| Registry record updated | July 24, 2025 |
| Trial ID | NCT06829381 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are undergoing One-Anastomosis Gastric Bypass.
✕Probably not a fit
Patients under 18, pregnant women, or those with prior bariatric surgery or short bowel syndrome may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of tailoring the length of the biliopancreatic limb (BPL) in One-Anastomosis Gastric Bypass (OAGB) surgery to the individual patient's total small bowel length. The goal is to determine if a personalized BPL length can lead to improved weight loss and metabolic outcomes compared to the standard fixed BPL length of 180 cm. By customizing the surgical approach, the study aims to minimize complications related to malabsorption while maximizing weight loss and health benefits for patients. Participants will be adults undergoing OAGB at the Tel-Aviv Sourasky Medical Center.
Why it matters
Potential benefit: If successful, this approach could lead to more effective weight loss and improved management of obesity-related conditions for patients.
How similar studies have gone: While the concept of tailoring surgical techniques is not novel, the specific approach of personalizing BPL length in OAGB has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years) undergoing OAGB Exclusion Criteria: * Patients \<18 years, pregnant women, or those lacking decision-making capacity Prior bariatric surgery Short bowel (\<450 cm)
Where it's running
-
Tel Aviv Sourasky Medical Center
Tel Aviv, Israel Recruiting
Study contacts
- Study coordinator: Adam Abu-Abeid, M.D
- Email: adama@tlvmc.gov.il
- Phone: +972524266283
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.