Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Personalized One Anastomosis Gastric Bypass for Weight Loss

Official title: Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial

Run by Tel-Aviv Sourasky Medical Center · NCT06829381 · Data updated 2026-11-12

This study is testing if customizing the length of a part of the stomach surgery can help adults lose more weight and improve their health compared to the standard length used in the procedure.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorTel-Aviv Sourasky Medical Center
Government
Locations1 site (Tel Aviv)
StatusRecruiting
StartedJanuary 29, 2025
Main results expectedJanuary 31, 2029
Study endsJanuary 31, 2029
Registry record updatedJuly 24, 2025
Trial IDNCT06829381 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are undergoing One-Anastomosis Gastric Bypass.

Probably not a fit

Patients under 18, pregnant women, or those with prior bariatric surgery or short bowel syndrome may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of tailoring the length of the biliopancreatic limb (BPL) in One-Anastomosis Gastric Bypass (OAGB) surgery to the individual patient's total small bowel length. The goal is to determine if a personalized BPL length can lead to improved weight loss and metabolic outcomes compared to the standard fixed BPL length of 180 cm. By customizing the surgical approach, the study aims to minimize complications related to malabsorption while maximizing weight loss and health benefits for patients. Participants will be adults undergoing OAGB at the Tel-Aviv Sourasky Medical Center.

Why it matters

Potential benefit: If successful, this approach could lead to more effective weight loss and improved management of obesity-related conditions for patients.

How similar studies have gone: While the concept of tailoring surgical techniques is not novel, the specific approach of personalizing BPL length in OAGB has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (≥18 years) undergoing OAGB

Exclusion Criteria:

* Patients \<18 years, pregnant women, or those lacking decision-making capacity Prior bariatric surgery Short bowel (\<450 cm)

Where it's running

  • Tel Aviv Sourasky Medical Center
    Tel Aviv, Israel
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.