Personalized One Anastomosis Gastric Bypass for Weight Loss
Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial
NA · Tel-Aviv Sourasky Medical Center · NCT06829381
This study is testing if customizing the length of a part of the stomach surgery can help adults lose more weight and improve their health compared to the standard length used in the procedure.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tel-Aviv Sourasky Medical Center (other gov) |
| Locations | 1 site (Tel Aviv) |
| Trial ID | NCT06829381 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of tailoring the length of the biliopancreatic limb (BPL) in One-Anastomosis Gastric Bypass (OAGB) surgery to the individual patient's total small bowel length. The goal is to determine if a personalized BPL length can lead to improved weight loss and metabolic outcomes compared to the standard fixed BPL length of 180 cm. By customizing the surgical approach, the study aims to minimize complications related to malabsorption while maximizing weight loss and health benefits for patients. Participants will be adults undergoing OAGB at the Tel-Aviv Sourasky Medical Center.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are undergoing One-Anastomosis Gastric Bypass.
Not a fit: Patients under 18, pregnant women, or those with prior bariatric surgery or short bowel syndrome may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective weight loss and improved management of obesity-related conditions for patients.
How similar studies have performed: While the concept of tailoring surgical techniques is not novel, the specific approach of personalizing BPL length in OAGB has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years) undergoing OAGB Exclusion Criteria: * Patients \<18 years, pregnant women, or those lacking decision-making capacity Prior bariatric surgery Short bowel (\<450 cm)
Where this trial is running
Tel Aviv
- Tel Aviv Sourasky Medical Center — Tel Aviv, Israel (RECRUITING)
Study contacts
- Study coordinator: Adam Abu-Abeid, M.D
- Email: adama@tlvmc.gov.il
- Phone: +972524266283
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Metabolic and Bariatric Surgery, one anastomosis gastric bypass, obesity, weight loss, tailoring