Personalized mobile app for cognitive behavioral therapy
Official title: Efficacy of Personalized Mobile Cognitive Behavioral Therapy Targeting Anxiety and Depression
Run by Weill Medical College of Cornell University · NCT05699525 · Data updated 2026-11-12
This study is testing if a personalized mobile app for cognitive behavioral therapy can help young people with anxiety, depression, or bipolar disorder just as much as a standard app.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 25 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Weill Medical College of Cornell University Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | August 2, 2024 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | May 22, 2026 |
| Trial ID | NCT05699525 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adolescents and young adults aged 18 to 25 with a primary diagnosis of anxiety, depression, or bipolar disorder.
✕Probably not a fit
Patients with a history of psychotic disorders, current manic episodes, or those already receiving cognitive behavioral therapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of a standard mobile cognitive behavioral therapy (CBT) program with a personalized version tailored to individual symptom profiles for adolescents and young adults experiencing anxiety, depression, or bipolar disorder. Participants will use the Maya app for two days a week over six weeks, engaging in assessments and optional MRI and EEG recordings. The goal is to determine if the personalized approach is as effective as the standard program while being less burdensome. The study aims to optimize mental health interventions that are easily accessible to young individuals.
Why it matters
Potential benefit: If successful, this approach could provide a more effective and accessible mental health intervention for young people struggling with anxiety and mood disorders.
How similar studies have gone: Other studies have shown promise in using mobile applications for mental health interventions, suggesting potential success for this personalized approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 25 years. * Primary diagnosis of an anxiety, depressive, or bipolar disorder as determined by a score of 4 or greater on the Clinical Severity Rating of the Anxiety Disorders Interview Schedule (ADIS). * If an individual is diagnosed with bipolar disorder, they must be currently euthymic or experiencing a depressive episode. * Access to an Apple iPhone, iPad, or Android device. Exclusion Criteria: * History of neurologic disorder that may affect the neural systems of interest or participant's ability to participate * Lifetime diagnosis of a psychotic disorder. * Current hypomanic or manic episode. * Currently in cognitive behavior therapy. * Change in dose of a psychiatric medication in the past 12 weeks. * Initiation of psychotherapy in the past 12 weeks. * Intent or plan to attempt suicide.
Where it's running
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Weill Cornell Medical College
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Jennifer Bress, Ph.D. — Weill Medical College of Cornell University
- Study coordinator: Maddy Schier
- Email: mas4019@med.cornell.edu
- Phone: (646) 289-5271
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.