Personalized genetic and biomarker approach for ALS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the genetic and biomarker profiles of patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) through a comprehensive approach. It will recruit 200 newly diagnosed ALS patients and perform genetic screening alongside biochemical and neuroradiological assessments to understand the disease's variability and progression. Patients will be classified based on specific ALS types and followed up regularly to monitor their clinical status and cognitive function. The study seeks to identify genetic variants that may influence ALS susceptibility and phenotypic differences.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of ALS

Exclusion Criteria:

* ALS patients under 18 years old

Where it's running

• IRCCS Istituto Auxologico Italiano
  Milan, Italy Recruiting
• Istituto di Ricerche Farmacologiche Mario Negri IRCCS
  Milan, Italy Recruiting
• Università degli Studi della Campania "Luigi Vanvitelli"
  Naples, Italy Recruiting
• AOU Citta della Salute e della Scienza di Torino
  Torino, Italy Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.