Clinical trial Recruiting at 1 site Observational Ages 18 and up

Personalized exercise program for cardiac outpatients

Official title: Efficacy of an Exercise-based Secondary Prevention Program in Patients With Stable Cardiovascular Disease

Run by Università degli Studi di Ferrara · NCT05817305 · Data updated 2026-11-12

This study is testing a personalized exercise program to see if it helps people with stable heart conditions improve their fitness and quality of life over time.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorUniversità degli Studi di Ferrara
Academic / other
Locations1 site (Ferrara, Ferrara)
StatusRecruiting
StartedJanuary 1, 1997
Main results expectedDecember 31, 2030
Study endsDecember 31, 2047
Registry record updatedApril 10, 2025
Trial IDNCT05817305 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with a history of cardiovascular events who are stable and able to participate in a physical activity program.

Probably not a fit

Patients with severe heart conditions, such as chronic heart failure or significant valvular disease, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the long-term effects of a personalized physical activity program on exercise capacity and quality of life in patients with stable cardiovascular disease. Participants will engage in a home training program that includes moderate-intensity aerobic activity for at least 30-60 minutes, 3-4 days a week. The study also evaluates the prognostic value of cardiovascular function through a walking test, focusing on survival, hospitalization, and medical costs. The program addresses clinical, socio-economic, and behavioral aspects, along with psychological support and risk factor management.

Why it matters

Potential benefit: If successful, this program could significantly improve the exercise capacity and quality of life for patients with cardiovascular diseases.

How similar studies have gone: Previous studies have shown that personalized exercise programs can lead to meaningful improvements in cardiovascular health, suggesting this approach is promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* the presence of one or more previous cardiovascular events

Exclusion Criteria:

* Ejection fraction \< 30%
* Chronic heart failure NYHA III-IV
* Severe aortic or mitral valvulopathy
* Severe physical or cognitive impairment
* Exercise-induced complex arrhythmias

Where it's running

  • Center for Exercise Science and Sport
    Ferrara, Ferrara, Italy
    Recruiting

Study contacts

  • Principal investigator: Giovanni Grazzi, Professor — Università degli Studi di Ferrara
  • Study coordinator: Giovanni Grazzi, Professor
  • Email: giovanni.grazzi@unife.it
  • Phone: +39 0535455963

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.