Comparing three shoulder nerve blocks for pain relief and breathing effects

Analgesic Efficacy and Respiratory Effects of Interscalene, Anterior Suprascapular, and Pericapsular Nerve Group Blocks in Shoulder Arthroscopy

Not applicable Interventional Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · NCT07429669

This study tests three different nerve blocks to see which best controls pain while preserving breathing after arthroscopic shoulder surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorAtatürk Chest Diseases and Chest Surgery Training and Research Hospital Academic / other
Locations1 site (Yenimahalle, Ankara)
Trial IDNCT07429669 on ClinicalTrials.gov

What this trial studies

The trial compares interscalene block, anterior suprascapular block, and a pericapsular nerve group (PENG) block in patients having elective arthroscopic shoulder surgery. Participants will receive one of the three regional anesthesia techniques and have postoperative pain and respiratory function, including diaphragmatic performance, monitored. The comparison aims to identify techniques that provide adequate analgesia without the phrenic nerve blockade and diaphragmatic dysfunction seen with interscalene blocks. The study is being conducted at Ankara Etlik City Hospital and enrolls adult surgical patients with ASA I–III who give informed consent.

Who should consider this trial

Good fit: Adults scheduled for elective arthroscopic shoulder surgery with ASA I–III who can give written consent and have no contraindications to regional anesthesia are ideal candidates.

Not a fit: Patients with contralateral phrenic nerve palsy, serious pulmonary disease, severe coagulopathy, infection at the block site, known allergy to local anesthetics, chronic opioid use, or neuropathic pain are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the findings could identify a nerve block approach that gives good postoperative pain relief with fewer breathing problems.

How similar studies have performed: Interscalene block is an established gold standard but is linked to diaphragmatic dysfunction, while some studies show anterior suprascapular blocks can provide sufficient analgesia and the shoulder PENG approach is a newer, less-tested alternative.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with ASA scores I-II-III
* Patients scheduled for elective arthroscopic shoulder surgery
* Patients who have been informed about the study and have given written consent will be included.

Exclusion Criteria:

* Those with a known allergy to local anesthetics
* Those with an infection at the application site
* Those with a severe coagulopathy disorder or anticoagulant use
* Those with contralateral phrenic nerve palsy or a serious pulmonary diagnosis
* Those with a history of chronic opioid use or neuropathic pain

Where this trial is running

Yenimahalle, Ankara

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative PainArthroscopic Shoulder SurgeryInterscalene blockAnterior suprascapular blockPericapsular nerve group blockShoulder BlockArthroscopic shoulder surgeryPain, acute
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.