Periodontal health in cigarette, e-cigarette, and narghile smokers

Evaluation of Periodontal Health Among Cigarette, Electronic Cigarettes, and Narghile Smokers Among a Sample of Alhawsh Private University Students

Observational Al-Hawash Private University · NCT07562295

This project tests whether cigarette, e-cigarette, or narghile use leads to different signs of gum disease in university student smokers.

Quick facts

Study typeObservational
Enrollment90 (estimated)
Ages18 Years to 25 Years
SexAll
SponsorAl-Hawash Private University Academic / other
Locations1 site (Homs, Homs Governorate)
Trial IDNCT07562295 on ClinicalTrials.gov

What this trial studies

This is a cross-sectional observational comparison of periodontal health among Al-Hawash Private University students who smoke only one product: traditional cigarettes, e-cigarettes, or narghile. Dental clinicians will record standard periodontal measures such as probing depth, clinical attachment loss, bleeding on probing, and plaque index, and participants will be classified by smoking type and exposure thresholds. The study excludes non-smokers, dual users, people over 25, those with systemic disease, recent antibiotic/steroid/NSAID use, or recent periodontal treatment. Statistical comparisons will test for significant differences in periodontal parameters between the three smoker groups.

Who should consider this trial

Good fit: Ideal candidates are Al-Hawash Private University students aged 25 or younger who smoke only one product (≥5 cigarettes/day for ≥1 year, or e-cigarette/narghile use ≥1 time/day for ≥1 year) and have no major systemic disease or recent relevant medications or dental treatment.

Not a fit: People unlikely to benefit include non-smokers, dual users of multiple tobacco products, those over 25, individuals with systemic diseases, or those who recently used antibiotics, steroids, NSAIDs, or received periodontal treatment.

Why it matters

Potential benefit: If successful, the results could clarify relative gum-health risks of cigarettes, e-cigarettes, and narghile for young smokers and inform prevention messaging.

How similar studies have performed: Previous research shows each smoking type can harm periodontal tissues, but direct head-to-head comparisons of cigarettes, e-cigarettes, and hookah in the same population are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Cigarette smokers: Individuals who have smoked five or more cigarettes per day for at least one year.
* E-cigarette smokers: Individuals who have smoked e-cigarettes one or more times per day for at least one year.
* narghile smokers: Individuals who have used a hookah one or more times per day for at least one year.

Exclusion Criteria:

* Non-smokers
* Ages older than 25 years
* Dual smokers: Individuals who smoke two or more types of tobacco.
* Individuals with systemic diseases, such as diabetes, heart disease, liver problems, and kidney disease
* Individuals who reported using antibiotics, steroids, or NSAIDs within the past month
* Individuals who have received periodontal treatment at least six months ago

Where this trial is running

Homs, Homs Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SmokersPeriodontal StatusSmokingCigarettesPeriodontal HealthElectronic CigarettesNarghile Smokers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.