PENG Block Compared with Femoral Nerve Block for Spinal Anesthesia in Hip Fracture Surgery
Official title: Comparison of Preoperative Pericapsular Nerve Group (PENG) Block Versus Femoral Nerve Block for Optimizing Spinal Anaesthesia in Proximal Femur Fracture Surgery: A Prospective Randomized Controlled Trial
Run by Taksim Egitim ve Arastirma Hastanesi · NCT07717463 · Data updated 2026-11-12
This trial tests whether the ultrasound-guided Pericapsular Nerve Group (PENG) block helps when positioning for spinal anesthesia in older adults with hip fractures, compared with the standard femoral nerve block.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 110 (estimated) |
| Sponsor | Taksim Egitim ve Arastirma Hastanesi Government |
| Locations | 2 sites (Istanbul, Beyoglu and 1 other locations) |
| Status | Recruiting |
| Started | July 22, 2026 |
| Main results expected | December 14, 2026 |
| Study ends | December 22, 2026 |
| Registry record updated | July 31, 2026 |
| Trial ID | NCT07717463 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 50 years or older with a proximal femoral fracture scheduled for surgical repair under spinal anesthesia and ASA I–III.
✕Probably not a fit
Patients who do not experience improved analgesia or easier positioning with PENG compared to femoral nerve block, or who have contraindications to regional anesthesia.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective randomized study compares two ultrasound-guided nerve blocks used before spinal anesthesia for proximal femur fractures in adults aged 50 and older. The aim is to see if the PENG block provides better pain control and easier positioning for spinal anesthesia than the traditional femoral nerve block. All participants receive spinal anesthesia with bupivacaine, and the trial evaluates technical performance, pain, and hemodynamic stability during the perioperative period. The study targets improving comfort and efficiency of the anesthesia process in elderly patients at risk for painful positioning and hemodynamic fluctuations.
Why it matters
Potential benefit: If successful, the PENG block could improve pain control and facilitate spinal anesthesia, potentially reducing procedural time and patient discomfort.
How similar studies have gone: Previous studies suggest PENG may offer analgesia with preserved motor function and potential benefits for anesthesia positioning, but direct comparisons to femoral nerve block in this setting are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 50 years or older. * Diagnosis of proximal femoral fracture. * Scheduled to undergo surgical repair under spinal anesthesia. * American Society of Anesthesiologists (ASA) physical status I-III. * Able to provide written informed consent. Exclusion Criteria: * Refusal to participate or inability to provide informed consent. * Coagulopathy or contraindication to spinal anesthesia or peripheral nerve block. * Local infection at the planned injection site. * Known allergy or hypersensitivity to local anesthetics. * Pre-existing neurological disease affecting lower extremity function or sensory assessment. * Cognitive impairment preventing reliable study participation or outcome assessment. * Previous lumbar spine surgery. * Polytrauma. * Body mass index (BMI) \<18 kg/m² or \>40 kg/m². * Current anticoagulant therapy that precludes neuraxial anesthesia or peripheral nerve block according to institutional practice.
Where it's running
-
Taksim Training and Research Hospital
Istanbul, Turkey (Türkiye) Recruiting -
Taksim Training and Research Hospital
Istanbul, Beyoglu, Turkey (Türkiye) Not yet recruiting
Study contacts
- Principal investigator: Celal Kaya — Taksim Training and Research Hospital
- Study coordinator: Celal Kaya, MD
- Email: c.kaya47@hotmail.com
- Phone: 90 5435176760
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.