Clinical trial Recruiting at 1 site Interventional Ages 50 and up

PENG Block Compared with Femoral Nerve Block for Spinal Anesthesia in Hip Fracture Surgery

Official title: Comparison of Preoperative Pericapsular Nerve Group (PENG) Block Versus Femoral Nerve Block for Optimizing Spinal Anaesthesia in Proximal Femur Fracture Surgery: A Prospective Randomized Controlled Trial

Run by Taksim Egitim ve Arastirma Hastanesi · NCT07717463 · Data updated 2026-11-12

This trial tests whether the ultrasound-guided Pericapsular Nerve Group (PENG) block helps when positioning for spinal anesthesia in older adults with hip fractures, compared with the standard femoral nerve block.

More Hip Fractures trials

Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment110 (estimated)
SponsorTaksim Egitim ve Arastirma Hastanesi
Government
Locations2 sites (Istanbul, Beyoglu and 1 other locations)
StatusRecruiting
StartedJuly 22, 2026
Main results expectedDecember 14, 2026
Study endsDecember 22, 2026
Registry record updatedJuly 31, 2026
Trial IDNCT07717463 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 50 years or older with a proximal femoral fracture scheduled for surgical repair under spinal anesthesia and ASA I–III.

Probably not a fit

Patients who do not experience improved analgesia or easier positioning with PENG compared to femoral nerve block, or who have contraindications to regional anesthesia.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized study compares two ultrasound-guided nerve blocks used before spinal anesthesia for proximal femur fractures in adults aged 50 and older. The aim is to see if the PENG block provides better pain control and easier positioning for spinal anesthesia than the traditional femoral nerve block. All participants receive spinal anesthesia with bupivacaine, and the trial evaluates technical performance, pain, and hemodynamic stability during the perioperative period. The study targets improving comfort and efficiency of the anesthesia process in elderly patients at risk for painful positioning and hemodynamic fluctuations.

Why it matters

Potential benefit: If successful, the PENG block could improve pain control and facilitate spinal anesthesia, potentially reducing procedural time and patient discomfort.

How similar studies have gone: Previous studies suggest PENG may offer analgesia with preserved motor function and potential benefits for anesthesia positioning, but direct comparisons to femoral nerve block in this setting are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 50 years or older.
* Diagnosis of proximal femoral fracture.
* Scheduled to undergo surgical repair under spinal anesthesia.
* American Society of Anesthesiologists (ASA) physical status I-III.
* Able to provide written informed consent.

Exclusion Criteria:

* Refusal to participate or inability to provide informed consent.
* Coagulopathy or contraindication to spinal anesthesia or peripheral nerve block.
* Local infection at the planned injection site.
* Known allergy or hypersensitivity to local anesthetics.
* Pre-existing neurological disease affecting lower extremity function or sensory assessment.
* Cognitive impairment preventing reliable study participation or outcome assessment.
* Previous lumbar spine surgery.
* Polytrauma.
* Body mass index (BMI) \<18 kg/m² or \>40 kg/m².
* Current anticoagulant therapy that precludes neuraxial anesthesia or peripheral nerve block according to institutional practice.

Where it's running

  • Taksim Training and Research Hospital
    Istanbul, Turkey (Türkiye)
    Recruiting
  • Taksim Training and Research Hospital
    Istanbul, Beyoglu, Turkey (Türkiye)
    Not yet recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.