Pelvic nerve mobilization for menstrual pain

Efficacy of Pelvic Nerve Mobilization in Reducing Symptoms of Primary Dysmenorrhea: A Randomized Controlled Trial

Not applicable Interventional University of Hail · NCT07354451

This study will test whether external pelvic nerve mobilization can reduce menstrual pain and related symptoms in university women aged 18–30 with primary dysmenorrhea.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 30 Years
SexFemale
SponsorUniversity of Hail Academic / other
Locations1 site (Sialkot)
Trial IDNCT07354451 on ClinicalTrials.gov

What this trial studies

Primary dysmenorrhea causes painful periods in the absence of identifiable pelvic disease and often leads to reduced quality of life and missed academic time. This single-blind, parallel-group randomized trial will randomly assign eligible women to receive either external pelvic nerve mobilization or a sham manual therapy across three consecutive menstrual cycles. The intervention is an entirely external, non-invasive physiotherapy technique intended to restore pelvic and lumbosacral nerve mobility and reduce neural sensitivity. Outcomes include pain intensity, menstrual distress, quality of life, pelvic tenderness, analgesic use, and academic absenteeism.

Who should consider this trial

Good fit: Ideal candidates are female university students aged 18–30 with regular cycles, a clinical diagnosis of primary dysmenorrhea, and average menstrual pain of 5 or greater on a visual analog scale.

Not a fit: Women with secondary causes of pelvic pain (for example endometriosis, fibroids, or pelvic inflammatory disease), prior pelvic or spinal surgery, neurological disorders, current pregnancy or lactation, or ongoing manual therapy are unlikely to benefit or are excluded from participation.

Why it matters

Potential benefit: If successful, this non-drug, non-invasive therapy could lower menstrual pain and improve daily functioning and attendance for young women with primary dysmenorrhea.

How similar studies have performed: There is some preliminary physiotherapy and neurodynamic evidence suggesting benefit for pelvic pain syndromes, but high-quality randomized trials specifically using external pelvic nerve mobilization for primary dysmenorrhea are limited, so the approach is relatively novel in this condition.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female university students aged 18-30 years
* Regular menstrual cycles (24-35 days)
* Clinically diagnosed primary dysmenorrhea
* Average menstrual pain intensity ≥ 5 on Visual Analog Scale
* Willingness to participate and provide informed consent

Exclusion Criteria:

* Secondary dysmenorrhea (e.g., endometriosis, fibroids, pelvic inflammatory disease)
* History of pelvic or spinal surgery
* Neurological disorders
* Current pregnancy or lactation
* Current physiotherapy or manual therapy treatment
* Contraindications to manual therapy

Where this trial is running

Sialkot

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Primary Dysmenorrhea
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.