Pelvic MRI to check organ mobility in endometriosis.
Official title: Study of Pelvic Organ Mobility by Dynamic MRI in Pelvic Endometriosis
Run by University Hospital, Lille · NCT05779462 · Data updated 2026-11-12
This project will use dynamic (cine) pelvic MRI to see if measuring pelvic organ movement helps diagnose and explain symptoms of endometriosis in women referred for pelvic MRI.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | Women only |
| Enrollment | 52 (estimated) |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 1 site (Lille) |
| Status | Recruiting |
| Started | May 23, 2023 |
| Main results expected | July 2026 |
| Study ends | July 2026 |
| Registry record updated | December 26, 2025 |
| Trial ID | NCT05779462 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are nulliparous women referred for suspected pelvic endometriosis who can provide written consent, have health insurance, and can comply with the imaging protocol.
✕Probably not a fit
Patients with BMI over 35, a history of major pelvic surgery or pelviperitonitis, hereditary connective tissue disorders, inability to undergo MRI, or who refuse consent are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational, single-center investigation using dynamic MRI sequences to measure pelvic organ mobility in women with suspected deep pelvic endometriosis. Participants will undergo cine MRI of the pelvis in addition to the usual pelvic MRI protocol to document relative organ movement. The study excludes patients with BMI >35, prior major pelvic surgery, pelviperitonitis, or hereditary connective tissue disease and requires written consent and health insurance coverage. Findings aim to improve preoperative lesion detection and to explore whether persistent hypo-mobility relates to symptoms or treatment failure.
Why it matters
Potential benefit: If successful, this could help clinicians detect endometriotic lesions before surgery and better tailor treatments by revealing reduced pelvic organ mobility linked to symptoms.
How similar studies have gone: Only a few small studies have used cine MRI to study pelvic organ mobility, so the approach has limited preliminary support but is not yet clinically validated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient referred for suspected pelvic endometriosis requiring pelvic MRI * Female, nulliparous, * patient with signed written consent, patient with health insurance, * patient willing to comply with all study procedures and duration Exclusion Criteria: * BMI \> 35, * history of hereditary collagen and elastic tissue disease, * history of pelviperitonitis, * history of major pelvic surgery, * inability to receive informed information, * inability to participate in the entire study, * lack of social security coverage, * refusal to sign consent
Where it's running
-
Service de chirurgie gynécologique Hôpital Jeanne de Flandre - CHU de LILLE
Lille, France Recruiting
Study contacts
- Principal investigator: Chrystele RUBOD, MD,PhD — University Hospital, Lille
- Study coordinator: Chrystele RUBOD, MD,PhD
- Email: chrystele.rubod@chru-lille.fr
- Phone: 0320445962
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.