Clinical trial Recruiting at 1 site Observational Ages 30 to 50 Women only

Pelvic floor muscle activity and urinary leakage in women with multiple sclerosis

Official title: FACTORS ASSOCIATED WITH URINARY INCONTINENCE AND EVALUATION OF PELVIC FLOOR MUSCLE ACTIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS: CROSS-SECTIONAL STUDY

Run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · NCT07489794 · Data updated 2026-11-12

This study will see if pelvic floor muscle activity measured with surface EMG is linked to how severe urinary leakage is in women with multiple sclerosis.

More Multiple Sclerosis trials

Quick facts

Study typeObservational
Ages30 Years to 50 Years
SexWomen only
Enrollment47 (estimated)
SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedMarch 9, 2026
Main results expectedSeptember 20, 2026
Study endsOctober 30, 2026
Registry record updatedMarch 24, 2026
Trial IDNCT07489794 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women aged 30–50 with multiple sclerosis (per 2017 McDonald criteria) who have urinary incontinence, EDSS below 6.5, stable medications for at least 6 months, and no communication barriers are ideal candidates.

Probably not a fit

People unlikely to benefit include men, women outside the 30–50 age range, those with EDSS ≥6.5, recent pregnancy or delivery, active urinary tract infection, pelvic organ prolapse, recent MS medication changes, or those unable to attend an in-person visit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cross-sectional study will enroll women with MS who report urinary incontinence and collect demographic and clinical data including MS type, disease duration, and EDSS score. Participants will complete standardized questionnaires on urinary symptoms, quality of life, physical activity, and fatigue. Pelvic floor muscle activity will be measured using surface electromyography (EMG) with biofeedback performed by trained physiotherapists. All assessments are completed in a single approximately 45-minute visit at the Pelvic Floor Health Center.

Why it matters

Potential benefit: If successful, findings could help tailor pelvic floor therapies and strategies to reduce urinary leakage and improve quality of life for women with MS.

How similar studies have gone: Surface EMG and questionnaire-based approaches have revealed altered pelvic floor activity in non-MS populations and small MS cohorts, but larger confirmatory studies are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Diagnosis of multiple sclerosis (MS) according to the 2017 revised McDonald criteria.

Female patients aged 30-50 years (age range with higher prevalence of urinary incontinence in MS).

Experiencing urinary incontinence (UI) symptoms according to the International Continence Society (ICS) definition.

EDSS (Expanded Disability Status Scale) score below 6.5.

Patients with no communication difficulties. -

Exclusion Criteria:

MS patients who do not provide consent to participate in the study.

MS patients who have had a medication change within the last 6 months.

Pregnant MS patients.

History of vaginal or cesarean delivery within the last 6 months.

Pelvic organ prolapse.

Urinary tract infection

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Where it's running

  • Istanbul, Prof. Dr. Cemil Taşçıoğlu City Hospital, Turkey
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.