Peer support intervention for depression in older adults with cognitive decline

Developing a Peer Support Intervention for Depression in SCD

Not applicable Interventional Massachusetts General Hospital · NCT06358404

This study is testing a new 8-week peer support program to see if it helps older adults with depression and memory issues feel better and improve their daily lives.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages60 Years and up
SexAll
SponsorMassachusetts General Hospital Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT06358404 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility, acceptability, and fidelity of an 8-week peer support intervention called PeersCOG for older adults aged 60 and above who experience depression and subjective cognitive decline. Thirty community-dwelling participants will receive depression care delivered by trained peer coaches through video chats and texts. The study will utilize mixed methods to assess outcomes related to depression, cognitive decline, functioning, and social factors at baseline, after 8 weeks, and at 3 months. Additionally, participants will involve a study partner to provide support and insights throughout the intervention.

Who should consider this trial

Good fit: Ideal candidates are older adults aged 60 and above who report subjective cognitive decline and depressive symptoms.

Not a fit: Patients with a current major depressive disorder or significant neurological conditions like mild cognitive impairment or Alzheimer's dementia may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide effective depression care tailored for older adults facing cognitive challenges.

How similar studies have performed: Other studies have shown promise in using peer support interventions for mental health, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Older adults aged 60+
* Endorse subjective cognitive decline
* Endorse depressive symptoms
* not currently experiencing suicidal ideation nor active, untreated manic, psychotic, or substance use disorder
* fluent in English and able to give informed consent

Exclusion Criteria:

* Meets diagnostic criteria for mild cognitive impairment or Alzheimer's dementia
* Meets diagnostic criteria for a current major depressive disorder
* have a history of neurological and psychiatric comorbidities such as major depressive disorder in the past 12 months

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Subjective Cognitive DeclineDepression in Old Age
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.