Pectoral nerve block versus thoracic paravertebral block to prevent chronic pain after mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adult women undergoing mastectomy under general anesthesia receive either an ultrasound-guided thoracic paravertebral block (TPVB) or pectoral nerve blocks (PEC I/II) in addition to standard postoperative analgesia, and their pain, shoulder function, and complications are followed after surgery. The trial enrolls patients aged 20–65 with BMI 25–35 and ASA I–III who are having unilateral mastectomy with or without axillary lymph node or sentinel node dissection. Ultrasound guidance is used to increase block accuracy and reduce complications, and outcomes include incidence of chronic post-mastectomy pain as well as acute analgesic effectiveness and adverse events. Follow-up includes postoperative pain assessments and longer-term evaluation for development of chronic pain.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA grade I, II, or III female patients in the age group of 20-65 years
* with body mass index (BMI) of 25-35 who were undergoing mastectomy with or without axillary lymph node or sentinel lymph node dissection or partial mastectomy (sparing the skin, areola, and nipple) with axillary lymph node dissection

Exclusion Criteria:

* male sex; patient refusal,
* a life expectancy less than 2 yr;
* active malignant disease; pregnant or breastfeeding women;
* bilateral surgery; ipsilateral breast surgery in the past 3 yr;

Where it's running

• Assiut governorate
  Asyut, Egypt Recruiting

Study contacts

• Study coordinator: Ghada Abo Elfadl
• Email: ghadafadl77@gmail.com
• Phone: 01005802086

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.