Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

Patient outcome reporting to speed PTSD diagnosis and care on Chicago's South Side

Official title: Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder

Run by University of Chicago · NCT06479447 · Data updated 2026-11-12

This project will try using patient portal outreach plus screening during primary care visits to find and connect adults with PTSD at two Chicago community health centers.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment17000 (estimated)
SponsorUniversity of Chicago
Academic / other
Locations2 sites (Chicago, Illinois and 1 other locations)
StatusRecruiting
StartedJuly 15, 2024
Main results expectedJuly 14, 2026
Study endsJuly 14, 2026
Registry record updatedNovember 10, 2025
Trial IDNCT06479447 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older who had an appointment at the participating CFHC clinics in the past 24 months and have not been screened for PTSD in the past 12 months.

Probably not a fit

Patients who were screened for PTSD within the last year, do not receive care at the participating clinics, or lack access to the patient portal are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

PORTAL-PTSD implements systematic PTSD screening in primary care clinics with high trauma prevalence, combining patient portal outreach and in-visit screening at Chicago Family Health Center sites on the South Side. The program targets adult patients who had a clinic visit in the past 24 months and have not been screened for PTSD in the last year. Investigators will track whether this population-health approach increases screening rates, identifies more patients with PTSD, and improves linkage to treatment compared with current practice. The approach builds on prior portal-based depression screening work and on clinic-based PTSD screening models used in high-risk settings.

Why it matters

Potential benefit: If successful, the approach could lead to earlier PTSD diagnosis and faster connection to treatment for patients in high-trauma communities.

How similar studies have gone: Similar portal-based screening increased detection of moderate-to-severe depression in prior work and clinic-visit PTSD screening is used in settings like the VA, but portal-based PTSD screening is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Patient Inclusion Criteria:

* Age ≥18 years
* Had an appointment at the study site in the last 24 months
* Were not screened for PTSD in the last 12 months

Exclusion Criteria:

* N/A

Where it's running

  • CFHC South Chicago
    Chicago, Illinois, United States
    Recruiting
  • CFHC Chicago Lawn
    Chicago, Illinois, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.