Parenting with 21‑hydroxylase congenital adrenal hyperplasia
Official title: Description of Parental Projects, Pregnancies and Pregnancy Outcomes in Patients With a Classic Form of 21-hydroxylase Deficiency
Run by Assistance Publique - Hôpitaux de Paris · NCT06900153 · Data updated 2026-11-12
This study uses phone questionnaires to see how 21‑hydroxylase CAH affects fertility, pregnancy outcomes, and parenting in adults with genetically confirmed disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 7 sites (Bordeaux and 6 other locations) |
| Status | Recruiting |
| Started | March 16, 2026 |
| Main results expected | March 16, 2027 |
| Study ends | March 16, 2027 |
| Registry record updated | August 31, 2026 |
| Trial ID | NCT06900153 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with genetically confirmed 21‑hydroxylase CAH who speak French, have French social security coverage, and can provide informed consent are ideal candidates.
✕Probably not a fit
Patients who are minors, lack genetic confirmation, do not speak French, are not covered by the French social security system, or are under legal protection may not be eligible or benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational study that collects reproductive, pregnancy, and parenting history by phone from adults with genetically confirmed 21‑hydroxylase congenital adrenal hyperplasia (CAH). Participants will be asked about fertility, pregnancy outcomes, prior genital surgery, hormonal treatment, and psychosocial factors affecting parenting. The study enrolls adults who can give informed consent and meet French administrative and language requirements. Data aim to describe real‑world experiences rather than test a drug or intervention.
Why it matters
Potential benefit: If successful, the results could improve counseling, clinical follow‑up, and support services for fertility, pregnancy care, and parenting needs in adults with 21‑hydroxylase CAH.
How similar studies have gone: Previous observational studies have documented fertility and pregnancy challenges in CAH but comprehensive, phone‑based data focused on parenting experiences remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 or over * Patients with HCS due to 21-hydroxylase deficiency, confirmed genetically * Patients who have been informed and do not object to participating in the research Exclusion Criteria: * Patients who do not speak French * Patients who are not affiliated to a social security scheme or who are not entitled to it * Patients under legal protection, or under guardianship or trusteeship.
Where it's running
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Hôpital Haut-Leveque-Service d'Endocrinologie
Bordeaux, France Recruiting -
Hospices Civiles de Lyon - Hôpital Femme Mère Enfant, Service Endocrinologie
Bron, France Recruiting -
CHIC- Service d'Endocrinologie
Créteil, France Recruiting -
AP-HP Hôpital Bicêtre - Service gynécologie Médicale
Le Kremlin-Bicêtre, France Recruiting -
AP-HP Hôpital Bicêtre, Service Endocrinologie
Le Kremlin-Bicêtre, France Recruiting -
Service d'endocrinologie, Hôpital Pitié Salpêtrière
Paris, France Recruiting
Show 1 more location
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Service d'endocrinologie, Hôpital Saint Antoine
Paris, France Recruiting
Study contacts
- Study coordinator: Anne BACHELOT
- Email: anne.bachelot@aphp.fr
- Phone: 01 42 16 02 46
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.