Parenting skills program for mothers with postpartum depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This longitudinal study investigates the effects of the Circle of Security Parenting (COSP) program on mothers experiencing postpartum depression. Over an 8-week period, participants will engage in remote sessions via Zoom, providing biological samples and completing assessments to evaluate changes in maternal depression symptoms, attachment styles, and infant social behaviors. The study aims to explore the biological mechanisms related to oxytocin receptor gene methylation and the impact of secure attachment on mother-infant relationships. Data will be collected at multiple time points to assess the efficacy of the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Mothers aged 18-50 years old with infants aged 3-14 months old
* Mothers who are experiencing symptoms of depression and mothers who are not experiencing symptoms of depression (non-depressed controls) are encouraged to participate.

(please note that mothers who are experiencing active depression and who are not already being treated under the care of a qualified healthcare provider (i.e. through therapy or psychopharmacological intervention) will be referred for such treatment prior to being enrolled in the study. This study is not a replacement for professional management of depression or other mental health symptoms.

Exclusion Criteria:

* Mothers with severe psychopathology (such as bipolar disorder, schizophrenia, personality disorders, among others)
* Infants with major medical problems that may interfere with a mother's ability to participate in and benefit from the intervention

Where it's running

• University of Colorado Denver
  Denver, Colorado, United States Recruiting

Study contacts

• Principal investigator: Sunny Stophaeros, MS — sunny.stophaeros@ucdenver.edu
• Study coordinator: Sunny Stophaeros, MS
• Email: sunny.stophaeros@ucdenver.edu
• Phone: 9253392971

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Smartphone-supported single-session psychotherapy for postpartum depression

  A single online therapy session plus four weeks of app-based support is being tested to see if it reduces depressive symptoms in postpartum women compared with a waitlist.

  Recruiting University of Sao Paulo · São Paulo, São Paulo · NCT07925762

• Midwife-Led Digital Follow-Up After Cesarean Delivery

  This trial tests whether a midwife-led, four-week digital follow-up after cesarean delivery improves mood, social support, and breastfeeding confidence compared with standard postpartum care.

  Recruiting Inonu University · Giresun · NCT07523932

• Tracking postpartum depression symptoms after starting zuranolone

  This study will see how postpartum depression symptoms change in people who start taking zuranolone within a year after giving birth.

  Recruiting Biogen · Cambridge, Massachusetts · NCT07398469

• Non-invasive zinc protoporphyrin screening for iron deficiency in pregnancy

  This project tests a handheld device that measures zinc protoporphyrin through the lower lip to detect iron deficiency in pregnant and recently postpartum people.

  Recruiting Wuerzburg University Hospital · Würzburg, Bavaria · NCT07083492

• Postpartum Depression: A Digital Decision Support Tool for Providers

  A digital tool within the electronic health record helps clinicians identify patients at risk for postpartum depression and guide support on referrals and education.

  Recruiting at 3 sites Weill Medical College of Cornell University · Brooklyn, New York and 3 other locations · NCT06818734

• Empowering mothers to prevent postpartum depression

  This study is testing a new online program that helps first-time pregnant women use art to boost their mental health and reduce the risk of postpartum depression.

  Recruiting Ege University · Izmir · NCT06787300

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.