Palliative care support at the start of pediatric phase 1 cancer trials
Official title: Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials
Run by Phoenix Children's Hospital · NCT07696065 · Data updated 2026-11-12
This study tests whether adding pediatric palliative care at the eligibility screening step helps families and clinicians during early-phase cancer trials for kids and young adults.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 0 Years to 25 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Phoenix Children's Hospital Academic / other |
| Locations | 3 sites (Phoenix, Arizona and 2 other locations) |
| Status | Recruiting |
| Started | July 10, 2026 |
| Main results expected | January 14, 2028 |
| Study ends | June 14, 2028 |
| Registry record updated | July 29, 2026 |
| Trial ID | NCT07696065 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Patients aged 0-25 with cancer who are being evaluated for enrollment in a pediatric or young adult phase 1 oncology trial, their caregivers, and their primary oncologists at participating sites.
✕Probably not a fit
Patients who do not experience distress or choose not to engage with PPC may see limited individual benefit from the intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-arm pilot study conducted at three major centers to see if pediatric palliative care (PPC) consultations can be integrated at the eligibility screening for children and young adults enrolling in phase 1 oncology trials. The study uses a longitudinal design and measures feasibility with caregiver and physician assessments, as well as recruitment and adherence metrics. The intervention focuses on PPC consultation during the screening process to address distress, decision-making, and care planning. Outcomes will inform whether broader implementation is practical across diverse hospital settings. The trial does not primarily test efficacy of a drug but evaluates care delivery processes to support patients and families.
Why it matters
Potential benefit: If feasible, adding PPC at screening could reduce family distress and improve decision-making while potentially improving overall experience during early-phase trials.
How similar studies have gone: Prior work in pediatric settings suggests PPC can support families during cancer care, but integration at trial eligibility screening is a novel, pilot approach here.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients (aged 0-25 years) diagnosed with cancer and undergoing evaluation for enrollment in a phase 1 trial, their caregivers, as well as their primary treating oncologist are eligible for study participation. Exclusion Criteria: * Previous palliative care exposure
Where it's running
-
Phoenix Children's Hospital
Phoenix, Arizona, United States Recruiting -
National Institutes of Health
Bethesda, Maryland, United States Not yet recruiting -
St. Jude Children's Research Hospital
Memphis, Tennessee, United States Not yet recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.